Background Cell transplantation offers a potential therapeutic approach to the repair and
regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI) …

An important factor to determine the success of stem cell therapy to the heart is the choice of
cell delivery route. This will affect the fate of donor cells and subsequently influence the …

Introduction Retrograde coronary venous infusion is a promising delivery method for cellular
cardiomyoplasty. Poor cell retention is the major obstacle to the establishment of this method …

Myocardial infarction (MI) is a major cause of morbidity and mortality worldwide. Until
recently, it was thought that myocardium was not able to repair itself, but studies have now …

Background: The role of serum metalloproteinases (MMP) after myocardial infarction (MI) is
unknown. Objective: The aim of this study was to evaluate the role of serum MMP-2 and-9 as …

Abstract Objectives Matrix metalloproteinases (MMPs) play an important role in the
pathogenesis of coronary artery disease (CAD). This study aims to determine the …

An important aspect of cell therapy in the field of cardiac disease is safe and effective
delivery of cells. Commonly used delivery strategies such as intramyocardial injection and …

Background Stem cell‐based therapy (SCT) is an important component of regenerative
therapy that brings hope to many patients. After decades of development, SCT has made …

Treatment of myocardial infarction (MI) with adipose-derived stem cells (ASCs) has
produced promising results. Cyclosporine A (CsA) inhibits apoptosis by preventing the …

Isolation and purification of stem cells and their delivery into diseased or aged tissues or
organs need special devices for proper transplantation of stem cells in order to achieve high …