The tremendous explosion in the field of MHC research in the last 5 years has significantly
advanced our understanding of antigen processing pathways, particularly with regard to …

This report summarizes the status of the comparative map for genes and anonymous loci
that have been mapped in mice and humans. Table 1 provides a listing of loci that compose …

The intracytoplasmic forms of class II (or Ia) major histocompatibility complex heterodimers
are associated with a third glycoprotein, termed the invariant chain (Ii). This specific …

Mice with tail kinks and deformities in their lower extremities were observed in a litter of C.
D2-Qa-2+ N6F15 mice. A mutant line that exhibits this phenotype in 100% of its offspring …

Data on loci whose positions are known in both man and mouse are presented in the form of
chromosomal displays, a table, and autosomal and X-chromosomal grids. At least 40 …

The invariant chain (Ii), a nonpolymorphic glycoprotein that associates with the
immunoregulatory Ia proteins encoded by the major histocompatibility complex, has a …

Comparative maps for mice and humans have been exceptionally important for predicting
linkages, for identifying homologous mutations and disease loci, and for studying genome …

We have developed a rapid method of generating and simultaneously mapping interrepeat
polymerase chain reaction products using DNA from interspecific backcross animals derived …

The invariant chain (Ii) is a glycoprotein coexpressed with the major histocompatibility
complex (MHC) class II antigens. Although Ii is encoded by a single gene unlinked to the …

We describe a method for isolating cosmid clones randomly from mouse chromosome 17. A
cosmid library was constructed from the mouse-Chinese hamster cell line R4 4-1 that …