Phosphorescent Ir (III) complexes have attracted abundant attention in biomedical research
due to their wide ranging properties and organelle specific intracellular imaging. Various …

One of the major constraints on the therapeutic use of oligonucleotides is inefficient delivery
to their sites of action in the cytosol or nucleus. Recently it has become evident that the …

Multimodal bioimaging is a powerful tool for visualizing the abnormal state at the target site
of the related disease. In this study, we used multimodal imaging techniques such as …

Chemically engineered nanomaterials have been extensively used in early tumor detection
and cancer therapy. Despite the promise shown, their chemical or exogenous nature …

Cancer is a life-threatening disease that has claimed the lives of many people worldwide.
With the current diagnostic methods, it is hard to determine cancer at an early stage, due to …

The problem of targeted delivery of antisense and siRNA oligonucleotides can be resolved
into two distinct aspects. The first concerns devising ligand-oligonucleotide or ligand-carrier …

The successful development of nanomaterials illustrates the considerable interest in the
development of new molecular probes for medical diagnosis and imaging. Substantial …

Realizing the promise of precision medicine in cancer therapy depends on identifying and
tracking cancerous growths to maximize treatment options and improve patient outcomes …

Doxorubicin is an antitumor drug commonly used against a wide spectrum of tumors.
However, the clinical application of DOX is restricted by its cardiotoxicity. To reduce the …

Purpose This study was aimed to develop doxorubicin-loaded quaternary ammonium
palmitoyl glycol chitosan (DOX–GCPQ) nanoformulation that could enable DOX delivery and …