Next-generation phenotyping: requirements and strategies for enhancing our understanding of genotype–phenotype relationships and its relevance to crop …

JN Cobb, G DeClerck, A Greenberg, R Clark… - Theoretical and Applied …, 2013 - Springer
More accurate and precise phenotyping strategies are necessary to empower high-
resolution linkage mapping and genome-wide association studies and for training genomic …

Systems-level analysis of mechanisms regulating yeast metabolic flux

SR Hackett, VRT Zanotelli, W Xu, J Goya, JO Park… - Science, 2016 - science.org
INTRODUCTION Metabolism is among the most strongly conserved processes across all
domains of life and is crucial for both bioengineering and disease research, yet we still have …

Gut microbiota dictates the metabolic response of Drosophila to diet

ACN Wong, AJ Dobson… - Journal of Experimental …, 2014 - journals.biologists.com
Animal nutrition is profoundly influenced by the gut microbiota, but knowledge of the scope
and core mechanisms of the underlying animal–microbiota interactions is fragmentary. To …

Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster Strains

JK Grenier, JR Arguello, MC Moreira… - G3: Genes …, 2015 - academic.oup.com
Reference collections of multiple Drosophila lines with accumulating collections of “omics”
data have proven especially valuable for the study of population genetics and complex trait …

Genetic correlation network prediction of forest soil microbial functional organization

B Ma, K Zhao, X Lv, W Su, Z Dai, JA Gilbert… - The ISME …, 2018 - academic.oup.com
Soil ecological functions are largely determined by the activities of soil microorganisms,
which, in turn, are regulated by relevant interactions between genes and their corresponding …

Correlated variation and population differentiation in satellite DNA abundance among lines of Drosophila melanogaster

KHC Wei, JK Grenier, DA Barbash… - Proceedings of the …, 2014 - National Acad Sciences
Tandemly repeating satellite DNA elements in heterochromatin occupy a substantial portion
of many eukaryotic genomes. Although often characterized as genomic parasites …

A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels

NJ Lanning, BD Looyenga, AL Kauffman, NM Niemi… - Cell reports, 2014 - cell.com
Altered cellular bioenergetics and mitochondrial function are major features of several
diseases, including cancer, diabetes, and neurodegenerative disorders. Given this important …

High-resolution inflorescence phenotyping using a novel image-analysis pipeline, PANorama

S Crowell, AX Falcão, A Shah, Z Wilson… - Plant …, 2014 - academic.oup.com
Variation in inflorescence development is an important target of selection for numerous crop
species, including many members of the Poaceae (grasses). In Asian rice (Oryza sativa) …

Metabolic pathways involved in Xin-Ke-Shu protecting against myocardial infarction in rats using ultra high-performance liquid chromatography coupled with …

Y Liu, H Jia, X Chang, W Cheng, X Zhao, G Ding… - … of Pharmaceutical and …, 2014 - Elsevier
Abstract Xin-Ke-Shu (XKS) is a patent drug used for coronary heart diseases in China. This
study evaluated the protective effect of XKS against isoproterenol (ISO)-induced myocardial …

Survey of Global Genetic Diversity Within the Drosophila Immune System

AM Early, JR Arguello, M Cardoso-Moreira… - Genetics, 2017 - academic.oup.com
Numerous studies across a wide range of taxa have demonstrated that immune genes are
routinely among the most rapidly evolving genes in the genome. This observation, however …