Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renal function. AKI is not considered a …

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have
been increasingly linked to both normal physiology and abnormal pathology in the kidney …

Perinatal asphyxia-induced brain injury may present as hypoxic-ischemic encephalopathy in
the neonatal period, and disability including cerebral palsy in the long term. The brain injury …

Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …

Background and aims Renal ischemia-reperfusion occurs in some clinical conditions such
as kidney surgery that can leads to acute renal failure. The aim of this study was to …

Bad water solubility and undesired toxicity of triptolide (TP) still restrict its clinical
applications in renal diseases. In this work, well-defined, monodispersed, and uniform-sized …

Deficient blood supply (ischemia) is a common consequence of some surgical procedures
and certain pathologies. Once blood circulation is re-established (reperfusion), a complex …

Matrix metalloproteinases (MMPs) are a group of zinc and calcium endopeptidases which
cleave extracellular matrix (ECM) proteins. They are also involved in the degradation of cell …

Matrix metalloproteinases (MMPs) are large family of proteinases. In addition to a
fundamental role in the remodeling of the extracellular matrix, they also cleave a number of …