The aim of this review article is to collate recent contributions of proteomic studies to cystic
fibrosis transmembrane conductance regulator (CFTR) biology. We summarize advances …

The highly complex and variable genotype–phenotype relationships observed in cystic
fibrosis (CF) have been an area of growing interest since the discovery of the CF …

Question In diseases such as asthma and cystic fibrosis (CF), the immune response is
dysregulated and the lung is chronically inflamed. Orai1 activation is required for the …

Trichomonas vaginalis is a common protozoan parasite, which causes trichomoniasis
associated with severe adverse reproductive outcomes. However, the underlying …

Background Cystic fibrosis (CF) neutrophils fail to eradicate infection despite their massive
recruitment into the lung. While studies mostly focus on pathogen clearance by normal …

The lipids are essential compounds of cells, with biochemical and structural properties.
Lipids are classified according to their chain length or saturation levels and biogenesis …

Models of CF have been developed in multiple organisms over the last 30 years to assist
with our understanding of disease pathophysiology. Ranging from fruit flies and zebrafish to …

Abstract In Cystic Fibrosis (CF) patients, cycles of infection and inflammation lead to fatal
lung damage. While diminished mucus clearance is restored by highly effective CFTR …

The number of studies related to detailed characteristics of immune system development in
early stages of ontogenesis are directed to expansion of concepts of mechanisms of …

Non-specific protection of the animal body are represented by various proteins and
peptides1. They are present in the various biological fluids and circulate in the blood of …