Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

Severe cases of COVID‐19 are associated with extensive lung damage and the presence of
infected multinucleated syncytial pneumocytes. The viral and cellular mechanisms …

The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

Extracellular vesicles (EVs), including exosomes, are thought to mediate intercellular
communication through the transfer of cargoes from donor to acceptor cells. Occurrence of …

Severe COVID‐19 is characterized by lung abnormalities, including the presence of
syncytial pneumocytes. Syncytia form when SARS‐CoV‐2 spike protein expressed on the …

Background Pregnant women are at increased risk for severe outcomes from coronavirus
disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity and …

Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. However,
the infectivity and pathological effects of ZIKV on placental trophoblast progenitor cells in …

During pregnancy the maternal–fetal interface plays vital roles in fetal development. Its
disruption is frequently found in pregnancy complications. Recent studies show increased …

Viral infections during pregnancy are associated with adverse pregnancy outcomes,
including maternal and fetal mortality, pregnancy loss, premature labor, and congenital …