Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome

V Pengo, G Denas, G Zoppellaro… - Blood, The Journal …, 2018 - ashpublications.org
Rivaroxaban is an effective and safe alternative to warfarin in patients with atrial fibrillation
and venous thromboembolism. We tested the efficacy and safety of rivaroxaban compared …

[HTML][HTML] Antiphospholipid antibodies in patients with COVID‐19: a relevant observation?

KMJ Devreese, EA Linskens, D Benoit… - Journal of Thrombosis …, 2020 - Elsevier
Background High incidence of thrombosis in COVID‐19 patients indicates a
hypercoagulable state. Hence, exploring the involvement of antiphospholipid antibodies …

Diagnosis and management of the antiphospholipid syndrome

D Garcia, D Erkan - New England Journal of Medicine, 2018 - Mass Medical Soc
Antiphospholipid Syndrome Antiphospholipid antibodies can induce endothelial-cell,
complement, platelet, neutrophil, and monocyte activation, leading to thrombosis, renal …

Rivaroxaban versus vitamin K antagonist in antiphospholipid syndrome: a randomized noninferiority trial

J Ordi-Ros, L Sáez-Comet… - Annals of internal …, 2019 - acpjournals.org
Background: The potential role of new oral anticoagulants in antiphospholipid antibody
syndrome (APS) remains uncertain. Objective: To determine whether rivaroxaban is …

Diagnosis, development, and treatment of portal vein thrombosis in patients with and without cirrhosis

NM Intagliata, SH Caldwell, A Tripodi - Gastroenterology, 2019 - Elsevier
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis,
but less frequently observed in patients without cirrhosis. Prompt diagnosis and …

Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

[HTML][HTML] Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised …

H Cohen, BJ Hunt, M Efthymiou… - The Lancet …, 2016 - thelancet.com
Background Rivaroxaban is established for the treatment and secondary prevention of
venous thromboembolism, but whether it is useful in patients with antiphospholipid …

[HTML][HTML] Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

KMJ Devreese, TL Ortel, V Pengo, B De Laat - Journal of thrombosis and …, 2018 - Elsevier
Currently, we use the classification criteria for antiphospholipid syndrome (APS) formulated
during the consensus conference in Sapporo and revised in Sydney 1. Classification criteria …