The effects of polyphenols and other bioactives on human health
Although deficiencies in polyphenol intake do not result in specific deficiency diseases,
adequate intake of polyphenols could confer health benefits, especially with regard to …
adequate intake of polyphenols could confer health benefits, especially with regard to …
Health benefits of resveratrol: Evidence from clinical studies
AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
MS Bonkowski, DA Sinclair - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
[HTML][HTML] Pleotropic effects of polyphenols in cardiovascular system
Numerous epidemiological and clinical studies demonstrate the beneficial effects of
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
Resveratrol and its human metabolites—effects on metabolic health and obesity
M Springer, S Moco - Nutrients, 2019 - mdpi.com
Resveratrol is one of the most widely studied polyphenols and it has been assigned a
plethora of metabolic effects with potential health benefits. Given its low bioavailability and …
plethora of metabolic effects with potential health benefits. Given its low bioavailability and …
Resveratrol and cardiovascular diseases
D Bonnefont-Rousselot - Nutrients, 2016 - mdpi.com
The increased incidence of cardiovascular diseases (CVDs) has stimulated research for
substances that could improve cardiovascular health. Among them, resveratrol (RES), a …
substances that could improve cardiovascular health. Among them, resveratrol (RES), a …
Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases
D Del Rio, A Rodriguez-Mateos… - Antioxidants & redox …, 2013 - liebertpub.com
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …
phenol-rich foods against chronic disease, including cardiovascular disease …
[HTML][HTML] Endothelial dysfunction—a major mediator of diabetic vascular disease
CM Sena, AM Pereira, R Seiça - … et Biophysica Acta (BBA)-molecular basis …, 2013 - Elsevier
The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
Resveratrol, metabolic syndrome, and gut microbiota
A Chaplin, C Carpéné, J Mercader - Nutrients, 2018 - mdpi.com
Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic
syndrome-related alterations in experimental animals, including glucose and lipid …
syndrome-related alterations in experimental animals, including glucose and lipid …
[HTML][HTML] The molecular targets of resveratrol
SS Kulkarni, C Cantó - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Resveratrol has emerged in recent years as a compound conferring strong protection
against metabolic, cardiovascular and other age-related complications, including …
against metabolic, cardiovascular and other age-related complications, including …