Over the past few decades, a range of vesicle-based drug delivery systems have entered
clinical practice and several others are in various stages of clinical translation. While most of …

The dermal route is an attractive route for vaccine delivery due to the easy skin accessibility
and a dense network of immune cells in the skin. The development of microneedles is …

Hepatitis E virus (HEV) is an important infection in humans in EU/EEA countries, and over
the last 10 years more than 21,000 acute clinical cases with 28 fatalities have been notified …

Introduction Vaccination remains very effective in stimulating protective immune responses
against infections. An important task in antibody and vaccine preparation is to choose an …

Nowadays, gold is used in (nano-) medicine, usually in the form of nanoparticles, due to the
solid proofs given of its therapeutic effects on several diseases. Gold also plays an important …

Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …

This study aimed to deliver mRNA vaccines and immune checkpoint blockers (ICB) with a
transcutaneous immunization (TCI) system based on ethosomes (ETH), exploring the …

The use of cancer vaccines is considered a promising therapeutic strategy in clinical
oncology, which is achieved by stimulating antitumor immunity with tumor antigens delivered …

The purpose of this study was to optimize the manufacturing of dissolving microneedles
(dMNs) and to increase the antigen loading in dMNs to investigate the effect on their …

Vaccines are a significant historical accomplishment in medical science due to its
significance in saving millions of lives around the world with a manifold decline in disease …