Impact of obesity on male fertility, sperm function and molecular composition
Male obesity in reproductive-age men has nearly tripled in the past 30 y and coincides with
an increase in male infertility worldwide. There is now emerging evidence that male obesity …
an increase in male infertility worldwide. There is now emerging evidence that male obesity …
All you need to know about sperm RNAs
J Santiago, JV Silva, J Howl… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Spermatogenesis generates a small and highly specialised type of cell that
is apparently incapable of transcription and translation. For many years, this dogma was …
is apparently incapable of transcription and translation. For many years, this dogma was …
A survey of small RNAs in human sperm
BACKGROUND There has been substantial interest in assessing whether RNAs (mRNAs
and sncRNAs, ie small non-coding) delivered from mammalian spermatozoa play a …
and sncRNAs, ie small non-coding) delivered from mammalian spermatozoa play a …
[HTML][HTML] The sperm nucleus: chromatin, RNA and the nuclear matrix
Within the sperm nucleus the paternal genome remains functionally inert and protected
following protamination. This is marked by a structural morphogenesis that is heralded by a …
following protamination. This is marked by a structural morphogenesis that is heralded by a …
Deleterious effects of obesity upon the hormonal and molecular mechanisms controlling spermatogenesis and male fertility
LM Davidson, K Millar, C Jones, M Fatum… - Human …, 2015 - Taylor & Francis
Worldwide obesity rates have nearly doubled since 1980 and currently over 10% of the
population is obese. In 2008, over 1.4 billion adults aged 20 years and older had a body …
population is obese. In 2008, over 1.4 billion adults aged 20 years and older had a body …
Small RNA sequencing of cryopreserved semen from single bull revealed altered miRNAs and piRNAs expression between High-and Low-motile sperm populations
E Capra, F Turri, B Lazzari, P Cremonesi, TM Gliozzi… - BMC genomics, 2017 - Springer
Abstract Background Small RNAs present in bovine ejaculate can be linked to sperm
abnormalities and fertility disorders. At present, quality parameters routinely used in semen …
abnormalities and fertility disorders. At present, quality parameters routinely used in semen …
Differential genes expression between fertile and infertile spermatozoa revealed by transcriptome analysis
Background It was believed earlier that spermatozoa have no traces of RNA because of loss
of most of the cytoplasm. Recent studies have revealed the presence of about 3000 different …
of most of the cytoplasm. Recent studies have revealed the presence of about 3000 different …
SpermBase: a database for sperm-borne RNA contents
Since their discovery approximately three decades ago, sperm-borne RNAs, both
large/small and coding/noncoding, have been reported in multiple organisms, and some …
large/small and coding/noncoding, have been reported in multiple organisms, and some …
A history of why fathers' RNA matters
Having been debated for many years, the presence and role of spermatozoal RNAs is
resolving, and their contribution to development is now appreciated. Data from different …
resolving, and their contribution to development is now appreciated. Data from different …
Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm
SE Pacheco, EA Houseman, BC Christensen… - PloS one, 2011 - journals.plos.org
Background In previous studies using candidate gene approaches, low sperm count
(oligospermia) has been associated with altered sperm mRNA content and DNA methylation …
(oligospermia) has been associated with altered sperm mRNA content and DNA methylation …