Immune checkpoint inhibitors in hepatocellular carcinoma: opportunities and challenges
X Liu, S Qin - The oncologist, 2019 - academic.oup.com
Hepatocellular carcinoma (HCC) is the most common malignancy worldwide, and is
especially common in China. A total of 70%–80% of patients are diagnosed at an advanced …
especially common in China. A total of 70%–80% of patients are diagnosed at an advanced …
ABC transporters: regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma
MP Ceballos, JP Rigalli, LI Ceré… - Current medicinal …, 2019 - ingentaconnect.com
For most cancers, the treatment of choice is still chemotherapy despite its severe adverse
effects, systemic toxicity and limited efficacy due to the development of multidrug resistance …
effects, systemic toxicity and limited efficacy due to the development of multidrug resistance …
[HTML][HTML] Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug …
Hepatocellular carcinoma (HCC) is a leading cause of cancer related deaths worldwide. It
was suggested that albendazole (ABZ) is a powerful inhibitor of several carcinoma types …
was suggested that albendazole (ABZ) is a powerful inhibitor of several carcinoma types …
MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53
The overexpression of the MDM2 oncoprotein frequently occurs in hepatocellular carcinoma
(HCC). Small molecules that inhibit MDM2-p53 binding show efficacy against p53 wild-type …
(HCC). Small molecules that inhibit MDM2-p53 binding show efficacy against p53 wild-type …
[HTML][HTML] Mechanisms of resistance to chemotherapy and radiotherapy in hepatocellular carcinoma
J Guo, L Li, B Guo, D Liu, J Shi, C Wu… - Translational Cancer …, 2018 - tcr.amegroups.org
Hepatocellular carcinoma (HCC) is an inflammation-related malignant tumor that develops
from underlying cirrhosis. As HCC is a common tumor seen in clinical practice, its prevention …
from underlying cirrhosis. As HCC is a common tumor seen in clinical practice, its prevention …
Carnosic acid induces apoptosis of hepatocellular carcinoma cells via ROS-mediated mitochondrial pathway
X Zhang, Y Chen, G Cai, X Li, D Wang - Chemico-Biological Interactions, 2017 - Elsevier
Carnosic acid (CA), an important bioactive phenolic diterpene mainly found in labiate plants,
exerts various biological functions, including antioxidant, anti-inflammatory, antitumor, and …
exerts various biological functions, including antioxidant, anti-inflammatory, antitumor, and …
[HTML][HTML] A novel inhibitor of MDM2 oncogene blocks metastasis of hepatocellular carcinoma and overcomes chemoresistance
Overexpression of the MDM2 oncogene and mutations in the p53 tumor suppressor
commonly occur in hepatocellular carcinoma (HCC) and are associated with increased …
commonly occur in hepatocellular carcinoma (HCC) and are associated with increased …
Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ …
Hepatocellular carcinoma (HCC) is characterized by bad prognosis and is the second most
common reason for cancer-linked mortality. Treatment with sorafenib (SRF) alone increases …
common reason for cancer-linked mortality. Treatment with sorafenib (SRF) alone increases …
Diagnostic accuracy of serum derived exosomes for hepatocellular carcinoma: A systematic review and meta-analysis
A Tiyuri, SS Baghermanesh… - Expert review of …, 2023 - Taylor & Francis
Introduction Early and non-invasive detection of hepatocellular carcinoma (HCC), which is
usually asymptomatic, can improve overall survival outcomes. The objective of this …
usually asymptomatic, can improve overall survival outcomes. The objective of this …
miRNA‑346 promotes proliferation, migration and invasion in liver cancer
Q Yu, X Yang, W Duan, C Li, Y Luo… - Oncology …, 2017 - spandidos-publications.com
Liver cancer primarily accounts for the majority of malignancies of the liver. MicroRNAs
(miRNAs) are endogenous non‑coding RNAs, which are important in tumorigenesis …
(miRNAs) are endogenous non‑coding RNAs, which are important in tumorigenesis …