A Review of Pseudomonas aeruginosa Metallophores: Pyoverdine, Pyochelin and Pseudopaline

G Ghssein, Z Ezzeddine - Biology, 2022 - mdpi.com
Simple Summary The human pathogen Pseudomonas aeruginosa (P. aeruginosa) causes
several infections, both acute and chronic, mainly in hosts with compromised immunity and …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

[HTML][HTML] FeGenie: a comprehensive tool for the identification of iron genes and iron gene neighborhoods in genome and metagenome assemblies

AI Garber, KH Nealson, A Okamoto… - Frontiers in …, 2020 - frontiersin.org
Iron is a micronutrient for nearly all life on Earth. It can be used as an electron donor and
electron acceptor by iron-oxidizing and iron-reducing microorganisms and is used in a …

[HTML][HTML] The biosynthesis of pyoverdines

MT Ringel, T Brüser - Microbial cell, 2018 - ncbi.nlm.nih.gov
Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for
growth under iron-limiting conditions. The production of pyoverdines by fluorescent …

Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa

GLA Mislin, IJ Schalk - Metallomics, 2014 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for
nosocomial infections. The prevalence of antibiotic-resistant P. aeruginosa strains is …

Pseudomonas aeruginosa and its multiple strategies to access iron

IJ Schalk, Q Perraud - Environmental Microbiology, 2023 - Wiley Online Library
Pseudomonas aeruginosa is a ubiquitous bacterium found in many natural and man‐made
environments. It is also a pathogen for plants, animals, and humans. As for almost all living …

Iron Acquisition in Mycobacterium tuberculosis

A Chao, PJ Sieminski, CP Owens… - Chemical …, 2018 - ACS Publications
The highly contagious disease tuberculosis (TB) is caused by the bacterium Mycobacterium
tuberculosis (Mtb), which has been evolving drug resistance at an alarming rate. Like all …

Iron acquisition in Pseudomonas aeruginosa by the siderophore pyoverdine: an intricate interacting network including periplasmic and membrane proteins

A Bonneau, B Roche, IJ Schalk - Scientific reports, 2020 - nature.com
Pyoverdine (PVDI) has been reported to act both as a siderophore for scavenging iron (a
key nutrient) and a signaling molecule for the expression of virulence factors. This …

Chemistry and biology of pyoverdines, Pseudomonas primary siderophores

C Cézard, N Farvacques… - Current medicinal …, 2015 - ingentaconnect.com
Pyoverdine is the generic name given to a vast family of fluorescent green-yellowish
pigments produced by Pseudomonas species. Pseudomonas aeruginosa is an opportunistic …

Fate of ferrisiderophores after import across bacterial outer membranes: different iron release strategies are observed in the cytoplasm or periplasm depending on the …

IJ Schalk, L Guillon - Amino acids, 2013 - Springer
Siderophore production and utilization is one of the major strategies deployed by bacteria to
get access to iron, a key nutrient for bacterial growth. The biological function of siderophores …