Biomaterial technology for tissue engineering applications

Y Tabata - Journal of the Royal Society interface, 2009 - royalsocietypublishing.org
Tissue engineering is a newly emerging biomedical technology and methodology to assist
and accelerate the regeneration and repairing of defective and damaged tissues based on …

The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs

W Wang, B Li, J Yang, L Xin, Y Li, H Yin, Y Qi, Y Jiang… - Biomaterials, 2010 - Elsevier
Poly (lactide-co-glycolide)(PLGA) sponge was filled with fibrin gel, bone marrow
mesenchymal stem cells (BMSCs) and transforming growth factor-β1 (TGF-β1) to obtain a …

In vivo restoration of full-thickness cartilage defects by poly (lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA …

W Wang, B Li, Y Li, Y Jiang, H Ouyang, C Gao - Biomaterials, 2010 - Elsevier
A composite construct comprising of bone marrow mesenchymal stem cells (BMSCs),
plasmid DNA encoding transforming growth factor-β1 (pDNA-TGF-β1), fibrin gel and poly …

Nonviral gene delivery to mesenchymal stem cells using cationic liposomes for gene and cell therapy

C Madeira, RD Mendes, SC Ribeiro… - BioMed Research …, 2010 - Wiley Online Library
Mesenchymal stem cells (MSCs) hold a great promise for application in several therapies
due to their unique biological characteristics. In order to harness their full potential in cell‐or …

Non-viral gene delivery of DNA polyplexed with nanoparticles transfected into human mesenchymal stem cells

JS Park, K Na, DG Woo, HN Yang, JM Kim, JH Kim… - Biomaterials, 2010 - Elsevier
Human mesenchymal stem cells (hMSCs) represent a potent target for gene delivery for
both stem cell differentiation applications and clinical therapies. However, it has, thus far …

Electroporation-advantages and drawbacks for delivery of drug, gene and vaccine

A Bolhassani, A Khavari, Z Orafa - Application of nanotechnology …, 2014 - books.google.com
Lack of potent drug and gene delivery is one of the major problems of cancer chemotherapy
and biotherapy. Different non-viral approaches have been proposed for drug and gene …

Polysaccharide multilayer nanoencapsulation of insulin-producing β-cells grown as pseudoislets for potential cellular delivery of insulin

Z Zhi, B Liu, PM Jones, JC Pickup - Biomacromolecules, 2010 - ACS Publications
This paper describes the use of a layer-by-layer nanocoating technique for the
encapsulation of insulin-producing pancreatic β-cell spheroids (pseudoislets) within …

Foxp3-modified bone marrow mesenchymal stem cells promotes liver allograft tolerance through the generation of regulatory T cells in rats

H Qi, G Chen, Y Huang, Z Si, J Li - Journal of Translational Medicine, 2015 - Springer
Background The transcription factor forkhead box P3 (Foxp3) is a master regulatory gene
necessary for the development and function of CD4+ CD25+ regulatory T cells (Tregs) …

Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8

A Voznesenskaya, PO Berggren… - … in bioengineering and …, 2023 - frontiersin.org
Genetic modification of pancreatic islet organoids, assembled in vitro prior to transplantation
is an emerging alternative to direct in vivo genetic manipulations for a number of clinical and …

Oscillating magnet array-based nanomagnetic gene transfection of human mesenchymal stem cells

A Fouriki, J Dobson - Nanomedicine, 2014 - Taylor & Francis
Aim: In this work, the potential of nanomagnetic transfection of primary human mesenchymal
stem cells (hMSCs) and the effects of a novel nonviral oscillating magnet array system in …