[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review

T Abu-Izneid, A Rauf, AA Khalil… - Critical reviews in …, 2022 - Taylor & Francis
Saffron (Crocus sativus L., family Iridaceae) is used traditionally for medicinal purpose in
Chinese, Ayurvedic, Persian and Unani medicines. The bioactive constituents such as …

Lactobacilli and bifidobacteria ameliorate memory and learning deficits and oxidative stress in β-amyloid (1–42) injected rats

S Athari Nik Azm, A Djazayeri, M Safa… - Applied Physiology …, 2018 - cdnsciencepub.com
The gastrointestinal microbiota affects brain function, including memory and learning. In this
study we investigated the effects of probiotics on memory and oxidative stress biomarkers in …

The neuroprotective potential of carotenoids in vitro and in vivo

J Manochkumar, CGP Doss, HR El-Seedi, T Efferth… - Phytomedicine, 2021 - Elsevier
Background Despite advances in research on neurodegenerative diseases, the
pathogenesis and treatment response of neurodegenerative diseases remain unclear …

[HTML][HTML] Association between chronic stress and Alzheimer's disease: Therapeutic effects of Saffron

M Saeedi, A Rashidy-Pour - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Chronic stress and high levels of glucocorticoids produce functional and structural changes
in brain and especially in the hippocampus, an important limbic system structure that plays a …

Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action

M Shafiee, S Arekhi, A Omranzadeh… - Journal of Affective …, 2018 - Elsevier
Background Depression and anxiety are two common mental health problems with high
economic and social costs. Currently, a number of treatments are available for patients with …

[HTML][HTML] Traditional Chinese medicine: role in reducing β-amyloid, apoptosis, autophagy, neuroinflammation, oxidative stress, and mitochondrial dysfunction of …

SY Chen, Y Gao, JY Sun, XL Meng, D Yang… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a progressive age-related neurodegenerative disease
characterized by memory loss and cognitive impairment. The major characteristics of AD are …

Novel tacrine-coumarin hybrids linked to 1, 2, 3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study

Z Najafi, M Mahdavi, M Saeedi… - Bioorganic …, 2019 - Elsevier
A new series of tacrine-coumarin hybrids linked to 1, 2, 3-triazole were designed,
synthesized, and tested as potent dual binding site cholinesterase inhibitors (ChEIs) for the …

[HTML][HTML] Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia

S Kouhestani, A Jafari, P Babaei - Neural Regeneration Research, 2018 - journals.lww.com
Alzheimer's disease (AD) is associated with oxidative stress, and ultimately results in
cognitive deficit. Despite existing literature on the pathophysiology of AD, there is currently …

[HTML][HTML] Natural compounds and autophagy: allies against neurodegeneration

A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …