Fatty liver disease is one of the major causes of morbidity and mortality worldwide. Fatty liver
includes non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis …

Breast cancer is the most common invasive malignancy in the world, with millions of
survivors living today. Type 2 diabetes mellitus (T2DM) is also a globally prevalent disease …

Importance Clinical studies confirm that obesity is a risk factor for recurrence in
postmenopausal women with hormone receptor–positive (HR+) breast cancer. Evidence …

Purpose Weight gain after breast cancer is common. The aim of this study was to determine
factors associated with weight gain after breast cancer in Australian women. Methods A …

Men are diagnosed with type 2 diabetes at lower body mass indexes than women; the role
of skeletal muscle in this sex difference is poorly understood. Type 2 diabetes impacts …

Background Weight gain is common after breast cancer. The aim of this study was to identify
and describe the barriers to and enablers of successful weight management for women with …

The obesity pandemic currently affects more than 70 million Americans and more than 650
million individuals worldwide. In addition to increasing susceptibility to pathogenic infections …

Dysregulation of estrogen receptor alpha (ERα) has been linked with increased metabolic
and cardiovascular disease risk. Here, we generate and characterize cardiomyocyte-specific …

Introduction Tamoxifen is a common treatment for estrogen receptor-positive breast cancer.
While tamoxifen treatment is generally accepted as safe, there are concerns about adverse …

Tamoxifen (TAM) is commonly administered to a variety of inducible or conditional
transgenic mice that contain Cre recombinase fused with ER. While the impacts of adult TAM …