DNA double-strand breaks (DSBs) are deleterious DNA lesions that if left unrepaired or are
misrepaired, potentially result in chromosomal aberrations, known drivers of carcinogenesis …

Cervical cancer (CaCx) is the deadliest malignancy among women which is caused by
human papillomavirus (HPV) and anthro-demographical/clinicopathological factors. HPV …

Expression of matrix metalloproteinase-1 (MMP1), an interstitial collagenase regulating the
extracellular matrix, plays a major role in carcinogenesis of gastric cancer, a leading cause …

BACKGROUND: Pelvic lymph node metastasis (PLNM) is an important prognostic factor for
patients with cervical carcinoma. The objective of this study was to identify a gene …

Splice isoform structure and abundance can be affected by either noncoding or
masquerading coding variants that alter the structure or abundance of transcripts. When …

Abstract Objectives/Hypothesis: The ataxia‐telangiectasia mutated (ATM) is thought to play
a major role in the caretaking of the overall genome stability, and its mutations have been …

The DNA repair gene Ku70, an important caretaker of the overall genome stability, is thought
to play a major role in the DNA double strand break repair system. It is known that defects in …

The aim of the present study was to evaluate the association between the polymorphisms of
the EXO1 gene and the risk of breast cancer in central Taiwan. Patients and Methods: In this …

The DNA double strand break repair gene XRCC4, an important caretaker of genome
stability and XRCC3 are suggested to play an imperative role in the development of …

Abstract Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair
system that contributes to the maintenance of genomic stability, modulation of DNA …