Exploring the genetic basis of early-onset chronic kidney disease
A Vivante, F Hildebrandt - Nature Reviews Nephrology, 2016 - nature.com
The primary causes of chronic kidney disease (CKD) in children differ from those of CKD in
adults. In the USA the most common diagnostic groups of renal disease that manifest before …
adults. In the USA the most common diagnostic groups of renal disease that manifest before …
Genetic, environmental, and epigenetic factors involved in CAKUT
N Nicolaou, KY Renkema, EMHF Bongers… - Nature Reviews …, 2015 - nature.com
Congenital anomalies of the kidney and urinary tract (CAKUT) refer to a spectrum of
structural renal malformations and are the leading cause of end-stage renal disease in …
structural renal malformations and are the leading cause of end-stage renal disease in …
Whole-exome sequencing identifies causative mutations in families with congenital anomalies of the kidney and urinary tract
AT Van Der Ven, DM Connaughton, H Ityel… - Journal of the …, 2018 - journals.lww.com
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are the most
prevalent cause of kidney disease in the first three decades of life. Previous gene panel …
prevalent cause of kidney disease in the first three decades of life. Previous gene panel …
[HTML][HTML] Overview of the cellular and molecular basis of kidney fibrosis
AA Eddy - Kidney international supplements, 2014 - Elsevier
The common pathogenetic pathway of progressive injury in patients with chronic kidney
disease (CKD) is epitomized as normal kidney parenchymal destruction due to scarring …
disease (CKD) is epitomized as normal kidney parenchymal destruction due to scarring …
Single-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humans
A Vivante, S Kohl, DY Hwang, GC Dworschak… - Pediatric …, 2014 - Springer
Congenital anomalies of the kidney and urinary tract (CAKUT) cover a wide range of
structural malformations that result from defects in the morphogenesis of the kidney and/or …
structural malformations that result from defects in the morphogenesis of the kidney and/or …
[HTML][HTML] Mutations in 12 known dominant disease-causing genes clarify many congenital anomalies of the kidney and urinary tract
DY Hwang, GC Dworschak, S Kohl, P Saisawat… - Kidney international, 2014 - Elsevier
Congenital anomalies of the kidney and urinary tract (CAKUT) account for approximately
half of children with chronic kidney disease. CAKUT can be caused by monogenic …
half of children with chronic kidney disease. CAKUT can be caused by monogenic …
Genetics of congenital anomalies of the kidney and urinary tract: the current state of play
VP Capone, W Morello, F Taroni, G Montini - International journal of …, 2017 - mdpi.com
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most frequent form of
malformation at birth and represent the cause of 40–50% of pediatric and 7% of adult end …
malformation at birth and represent the cause of 40–50% of pediatric and 7% of adult end …
Wnt signaling and the control of human stem cell fate
JK Van Camp, S Beckers, D Zegers… - Stem Cell Reviews and …, 2014 - Springer
Wnt signaling determines major developmental processes in the embryonic state and
regulates maintenance, self-renewal and differentiation of adult mammalian tissue stem …
regulates maintenance, self-renewal and differentiation of adult mammalian tissue stem …
Novel insights into the pathogenesis of monogenic congenital anomalies of the kidney and urinary tract
AT van der Ven, A Vivante… - Journal of the American …, 2018 - journals.lww.com
Congenital anomalies of the kidneys and urinary tract (CAKUT) comprise a large spectrum
of congenital malformations ranging from severe manifestations, such as renal agenesis, to …
of congenital malformations ranging from severe manifestations, such as renal agenesis, to …
CKD-induced wingless/Integration1 inhibitors and phosphorus cause the CKD–mineral and bone disorder
Y Fang, C Ginsberg, M Seifert, O Agapova… - Journal of the …, 2014 - journals.lww.com
In chronic kidney disease, vascular calcification, renal osteodystrophy, and phosphate
contribute substantially to cardiovascular risk and are components of CKD–mineral and …
contribute substantially to cardiovascular risk and are components of CKD–mineral and …