The median-effect equation derived from the mass-action law principle at equilibrium-steady
state via mathematical induction and deduction for different reaction sequences and …

A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive
immune response. The widely held view has been that the great variability of viral …

A recombinant virus assay was used to characterize in detail neutralizing antibody
responses directed at circulating autologous HIV in plasma. Examining serial plasma …

The development of a rapid and efficient system to identify human immunodeficiency virus
type 1 (HIV-1)-infected individuals with broad and potent HIV-1-specific neutralizing …

Licensed vaccines against viral diseases generate antibodies that neutralize the infecting
virus and protect against infection or disease. Similarly, an effective vaccine against HIV-1 …

The glycoprotein (gp) 120 subunit is an important part of the envelope spikes that decorate
the surface of HIV-1 and a major target for neutralizing antibodies. However, immunization …

Maternal passive immunity typically plays a critical role in protecting infants from new
infections; however, the specific contribution of neutralizing antibodies in limiting mother-to …

The development of a highly effective AIDS vaccine will likely depend on success in
designing immunogens that elicit broadly neutralizing antibodies to naturally circulating …

Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …

Alanine scanning mutagenesis was performed on monomeric gp120 of human
immunodeficiency virus type 1 to systematically identify residues important for gp120 …