[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Current and emerging therapies for corneal neovascularization

D Roshandel, M Eslani, A Baradaran-Rafii… - The ocular …, 2018 - Elsevier
The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

High-risk corneal transplantation: recent developments and future possibilities

WJ Armitage, C Goodchild, MD Griffin, DJ Gunn… - …, 2019 - journals.lww.com
Human corneal transplantation (keratoplasty) is typically considered to have superior short-
and long-term outcomes and lower requirement for immunosuppression compared to solid …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

The novel role of lymphatic vessels in the pathogenesis of ocular diseases

T Clahsen, K Hadrian, M Notara, SL Schlereth… - Progress in Retinal and …, 2023 - Elsevier
Historically, the eye has been considered as an organ free of lymphatic vessels. In recent
years, however, it became evident, that lymphatic vessels or lymphatic-like vessels …

[HTML][HTML] Future directions in managing aniridia-associated keratopathy

AJH Van Velthoven, TP Utheim, M Notara… - Survey of …, 2023 - Elsevier
Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia
and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal …

[HTML][HTML] 5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways …

J Xie, S Wang, Z Li, C Ao, J Wang, L Wang… - … of Photochemistry and …, 2019 - Elsevier
Human papillomavirus (HPV) infection is linked to several diseases, the most prominent of
which are cervical cancer and genital condyloma acuminatum. Previous studies have …

[HTML][HTML] UV light crosslinking regresses mature corneal blood and lymphatic vessels and promotes subsequent high-risk corneal transplant survival

Y Hou, VNH Le, G Tóth, S Siebelmann… - American Journal of …, 2018 - Elsevier
Immunologic graft rejection is the main complication after corneal transplant into
pathologically prevascularized so-called high-risk eyes. The aim of this study was to …

Third-party allogeneic mesenchymal stromal cells prevent rejection in a pre-sensitized high-risk model of corneal transplantation

P Lohan, N Murphy, O Treacy, K Lynch… - Frontiers in …, 2018 - frontiersin.org
High-risk cornea transplant recipients represent a patient population with significant un-met
medical need for more effective therapies to prevent immunological graft rejection due to …

Corneal crosslinking to regress pathologic corneal neovascularization before high-risk keratoplasty

F Schaub, Y Hou, W Zhang, F Bock, D Hos… - Cornea, 2021 - journals.lww.com
Purpose: Corneal neovascularization is the main risk factor for graft rejection after high-risk
penetrating keratoplasty (PK). Corneal crosslinking (CXL) has been shown to regress …