Decoding how tissue properties emerge across multiple spatial and temporal scales from
the integration of local signals is a grand challenge in quantitative biology. For example, the …

The robust specification of organ development depends on coordinated cell-cell
communication. This process requires signal integration among multiple pathways, relying …

Calcium signaling plays a crucial role in the physiology of the organs but also in various
aspects of the organogenesis of the embryo. High versatility of calcium signaling is encoded …

Epithelial tissues in many contexts can be viewed as soft active solids. Their active nature is
manifested in the ability of individual cells within the tissue to contract and/or remodel their …

Understanding organ development requires an understanding of how individual cells make
decisions, and how those decisions integrate into system-wide properties. However, in many …