Iron is essential for many biological functions and iron deficiency and overload have major
health implications. We performed a meta-analysis of three genome-wide association …

Detailed knowledge of how diversity in the sequence of the human genome affects
phenotypic diversity depends on a comprehensive and reliable characterization of both …

Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed
a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and …

Migraine is a complex neurovascular disease with a range of severity and symptoms, yet
mostly studied as one phenotype in genome-wide association studies (GWAS). Here we …

People with kidney disease are disproportionately affected by atherosclerosis for unclear
reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived …

Biobank research may lead to an improved understanding of disease etiology and advance
personalized medicine. Denmark (population~ 5.9 million) provides a unique setting for …

The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic
basis remains largely unresolved. We present a maternal genome-wide meta-analysis of …

Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or
ACPA positive) and seronegative subsets. Methods We performed a genome-wide …

Back pain is a common and debilitating disorder with largely unknown underlying biology.
Here we report a genome-wide association study of back pain using diagnoses assigned in …

Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often
described as an unpleasant sensation associated with an urge to move the legs. Here we …