Bone morphogenetic proteins, carriers, and animal models in the development of novel bone regenerative therapies
Bone morphogenetic proteins (BMPs) possess a unique ability to induce new bone
formation. Numerous preclinical studies have been conducted to develop novel, BMP-based …
formation. Numerous preclinical studies have been conducted to develop novel, BMP-based …
A systematic review of bone marrow stromal cells and periosteum-derived cells for bone regeneration
Bone marrow stromal cells (BMSCs) and periosteum-derived cells (PDCs) represent
promising skeletal stem cell sources to treat critical-size bone defects. However, the large …
promising skeletal stem cell sources to treat critical-size bone defects. However, the large …
Patterned, organoid-based cartilaginous implants exhibit zone specific functionality forming osteochondral-like tissues in vivo
GN Hall, WL Tam, KS Andrikopoulos, L Casas-Fraile… - Biomaterials, 2021 - Elsevier
Tissue engineered constructs have the potential to respond to the unmet medical need of
treating deep osteochondral defects. However, current tissue engineering strategies …
treating deep osteochondral defects. However, current tissue engineering strategies …
Construction and biocompatibility evaluation of fibroin/sericin-based scaffolds
Z Fu, W Li, J Wei, K Yao, Y Wang, P Yang… - ACS Biomaterials …, 2022 - ACS Publications
Because tissue responses to implants determine the success or failure of tissue engineering
products, fibroin/sericin-based scaffolds including bionic silk scaffolds, native silk fibers …
products, fibroin/sericin-based scaffolds including bionic silk scaffolds, native silk fibers …
[HTML][HTML] Autologous bone graft substitute containing rhBMP6 within autologous blood coagulum and synthetic ceramics of different particle size determines the …
Bone morphogenetic proteins (BMPs) are potent osteoinductive agents for bone tissue
engineering. In order to define optimal properties of a novel autologous bone graft substitute …
engineering. In order to define optimal properties of a novel autologous bone graft substitute …
Potential of periosteal cells in bone and cartilage regeneration: a systematic review
R Cao, B Chen, Q Li, P Qiu, X Liang… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: The unavailability of adequate human primary cells presents multiple
challenges in terms of bone and cartilage regeneration and disease modeling experiments …
challenges in terms of bone and cartilage regeneration and disease modeling experiments …
[HTML][HTML] NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis
T Ma, Y Chen, ZG Yi, J Liu, YH Li, J Bai, WT Tie… - Cellular …, 2022 - Elsevier
Multiple myeloma (MM) is one of the most common tumors of the hematological system and
remains incurable. Recent studies have shown that long noncoding RNA NORAD is a …
remains incurable. Recent studies have shown that long noncoding RNA NORAD is a …
Periodontal tissue regeneration by recombinant human collagen peptide granules applied with β-tricalcium phosphate fine particles
Y Yoshino, H Miyaji, E Nishida, Y Kanemoto… - Journal of Oral …, 2023 - Elsevier
Objectives Recombinant human collagen peptide (RCP) is a recombinantly created xeno-
free biomaterial enriched in arginine-glycine-aspartic acid sequences with good …
free biomaterial enriched in arginine-glycine-aspartic acid sequences with good …
[HTML][HTML] Developmental engineering of living implants for deep osteochondral joint surface defects
LF Mendes, K Bosmans, I Van Hoven, SR Viseu… - Bone, 2020 - Elsevier
Introduction The repair of deep osteochondral joint surface defects represents a significant
unmet clinical need. Importantly, untreated lesions lead to a high rate of osteoarthritis. The …
unmet clinical need. Importantly, untreated lesions lead to a high rate of osteoarthritis. The …