Turmeric and its major compound curcumin on health: bioactive effects and safety profiles for food, pharmaceutical, biotechnological and medicinal applications

J Sharifi-Rad, YE Rayess, AA Rizk, C Sadaka… - Frontiers in …, 2020 - frontiersin.org
Curcumin, a yellow polyphenolic pigment from the Curcuma longa L.(turmeric) rhizome, has
been used for centuries for culinary and food coloring purposes, and as an ingredient for …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Curcumin: an orally bioavailable blocker of TNF and other pro‐inflammatory biomarkers

BB Aggarwal, SC Gupta, B Sung - British journal of …, 2013 - Wiley Online Library
TNFs are major mediators of inflammation and inflammation‐related diseases, hence, the U
nited S tates F ood and D rug A dministration (FDA) has approved the use of blockers of the …

Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

W Xie, L Du - Diabetes, obesity and metabolism, 2011 - Wiley Online Library
Diabetes is usually associated with inflammation. Inflammation contributes to the
development of diabetes. Traditional Chinese medicines (TCM) play an important role in …

[HTML][HTML] Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect

G Tsuji, M Takahara, H Uchi, T Matsuda, T Chiba… - Journal of Investigative …, 2012 - Elsevier
Ketoconazole (KCZ) has been shown to exhibit anti-inflammatory effects in addition to its
inhibitory effects against fungi; however, the underlying molecular mechanism remains …

Effect of curcumin nanomicelle on the clinical symptoms of patients with rheumatoid arthritis: A randomized, double‐blind, controlled trial

M Javadi, H Khadem Haghighian… - … journal of rheumatic …, 2019 - Wiley Online Library
Aim Rheumatoid arthritis (RA) is a systemic inflammatory disease. In recent years, new
drugs with novel targets have been developed to increase the efficacy of drugs in the …

Effects of a nutritional supplement in dogs affected by osteoarthritis

N Musco, G Vassalotti, V Mastellone… - Veterinary medicine …, 2019 - Wiley Online Library
Osteoarthritis is a form of chronic joint inflammation caused by the deterioration of the joint
cartilage, accompanied by chronic pain, lameness and stiffness, particularly after prolonged …

Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide: translocation of nuclear factor-κB as potential target

F Zhao, Y Gong, Y Hu, M Lu… - Molecular …, 2015 - spandidos-publications.com
The aim of the present study was to investigate and compare the anti‑inflammatory activities
of curcumin and its three metabolites, tetrahydrocurcumin, hexahydrocurcumin and …

The antinociceptive and anti-inflammatory effects of Salvia officinalis leaf aqueous and butanol extracts

EY Qnais, M Abu-Dieyeh, FA Abdulla… - Pharmaceutical …, 2010 - Taylor & Francis
Context: The leaf of sage Salvia officinalis L.(Lamiaceae) is reputed in the folk medicine of
Arabia, and Jordan in particular, to relieve pain associated with gastrointestinal disturbance …

Synergistic effect of the interaction between curcumin and diclofenac on the formalin test in rats

MA De Paz-Campos, MI Ortiz, AEC Piña… - Phytomedicine, 2014 - Elsevier
The association of non-steroidal anti-inflammatory drugs with certain plant extracts can
increase antinociceptive activity, permitting the use of lower doses and thus limiting side …