[HTML][HTML] Biologics for tendon repair

D Docheva, SA Müller, M Majewski… - Advanced drug delivery …, 2015 - Elsevier
Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

Tendon injury: from biology to tendon repair

G Nourissat, F Berenbaum, D Duprez - Nature Reviews Rheumatology, 2015 - nature.com
Tendon is a crucial component of the musculoskeletal system. Tendons connect muscle to
bone and transmit forces to produce motion. Chronic and acute tendon injuries are very …

Self‐healing hydrogel embodied with macrophage‐regulation and responsive‐gene‐silencing properties for synergistic prevention of peritendinous adhesion

C Cai, X Zhang, Y Li, X Liu, S Wang, M Lu… - Advanced …, 2022 - Wiley Online Library
Antiadhesion barriers such as films and hydrogels used to wrap repaired tendons are
important for preventing the formation of adhesion tissue after tendon surgery. However …

[HTML][HTML] Flexible electrical stimulation device with Chitosan-Vaseline® dressing accelerates wound healing in diabetes

XF Wang, ML Li, QQ Fang, WY Zhao, D Lou, YY Hu… - Bioactive materials, 2021 - Elsevier
The healing process of diabetic wounds is typically disordered and prolonged and requires
both angiogenesis and epithelialization. Disruptions of the endogenous electric fields (EFs) …

The cellular basis of fibrotic tendon healing: challenges and opportunities

AEC Nichols, KT Best, AE Loiselle - Translational Research, 2019 - Elsevier
Tendon injuries are common and can dramatically impair patient mobility and productivity,
resulting in a significant socioeconomic burden and reduced quality of life. Because the …

Tendon biomechanics and mechanobiology—a minireview of basic concepts and recent advancements

JHC Wang, Q Guo, B Li - Journal of hand therapy, 2012 - Elsevier
Due to their unique hierarchical structure and composition, tendons possess characteristic
biomechanical properties, including high mechanical strength and viscoelasticity, which …

Reparative and maladaptive inflammation in tendon healing

V Arvind, AH Huang - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
Tendon injuries are common and debilitating, with non-regenerative healing often resulting
in chronic disease. While there has been considerable progress in identifying the cellular …

Tendon development and musculoskeletal assembly: emerging roles for the extracellular matrix

A Subramanian, TF Schilling - Development, 2015 - journals.biologists.com
Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …

Advances in biomaterials for preventing tissue adhesion

W Wu, R Cheng, J das Neves, J Tang, J Xiao… - Journal of controlled …, 2017 - Elsevier
Adhesion is one of the most common postsurgical complications, occurring simultaneously
as the damaged tissue heals. Accompanied by symptoms such as inflammation, pain and …

Advanced technology-driven therapeutic interventions for prevention of tendon adhesion: Design, intrinsic and extrinsic factor considerations

Q Zhang, Y Yang, L Yildirimer, T Xu, X Zhao - Acta biomaterialia, 2021 - Elsevier
Tendon adhesion formation describes the development of fibrotic tissue between the tendon
and its surrounding tissues, which commonly occurs as a reaction to injury or surgery. Its …