Systems serology detects functionally distinct coronavirus antibody features in children and elderly
The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared
to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses …
to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses …
Comparison of seroconversion in children and adults with mild COVID-19
ZQ Toh, J Anderson, N Mazarakis, M Neeland… - JAMA network …, 2022 - jamanetwork.com
Importance The immune response in children with SARS-CoV-2 infection is not well
understood. Objective To compare seroconversion in nonhospitalized children and adults …
understood. Objective To compare seroconversion in nonhospitalized children and adults …
IgG3 and IgM identified as key to SARS-CoV-2 neutralization in convalescent plasma pools
C Kober, S Manni, S Wolff, T Barnes, S Mukherjee… - PLoS …, 2022 - journals.plos.org
Analysis of convalescent plasma derived from individuals has shown that IgG3 has the most
important role in binding to SARS-CoV-2 antigens; however, this has not yet been confirmed …
important role in binding to SARS-CoV-2 antigens; however, this has not yet been confirmed …
Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina
RE Chahla, RH Tomas-Grau, SI Cazorla… - The Lancet Regional …, 2022 - thelancet.com
Summary Background Gam-COVID-Vac (SPUTNIK V) has been granted emergency use
authorization in 70 nations and has been administered to millions worldwide. However …
authorization in 70 nations and has been administered to millions worldwide. However …
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity
Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune …
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune …
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we
found that Australian First Nations peoples elicit effective immune responses to COVID-19 …
found that Australian First Nations peoples elicit effective immune responses to COVID-19 …
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Immunocompromised hematology patients are vulnerable to severe COVID-19 and respond
poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 …
poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 …
Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine
LM Weskamm, A Fathi, MP Raadsen, AZ Mykytyn… - Cell Reports …, 2022 - cell.com
Summary The Middle East respiratory syndrome (MERS) is a respiratory disease caused by
MERS coronavirus (MERS-CoV). In follow up to a phase 1 trial, we perform a longitudinal …
MERS coronavirus (MERS-CoV). In follow up to a phase 1 trial, we perform a longitudinal …
[HTML][HTML] Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations
Pregnancy poses a greater risk for severe COVID-19; however, underlying immunological
changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined …
changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined …
Correlation between in vitro neutralization assay and serological tests for protective antibodies detection
MA Bonifacio, R Laterza, A Vinella, A Schirinzi… - International Journal of …, 2022 - mdpi.com
Serological assays are useful in investigating the development of humoral immunity against
SARS-CoV-2 in the context of epidemiological studies focusing on the spread of protective …
SARS-CoV-2 in the context of epidemiological studies focusing on the spread of protective …