Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

Virus-like particles are supra-molecular assemblages, usually icosahedral or rod-like
structures. They incorporate key immunologic features of viruses which include repetitive …

Vaccine efforts to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), which is responsible for the current coronavirus disease 2019 (COVID-19) pandemic, are …

Structures of BG505 SOSIP. 664 trimer in complex with broadly neutralizing antibodies
(bNAbs) have revealed the critical role of trimeric context for immune recognition of HIV-1 …

Virus-like particles (VLPs) consist of viral structural proteins that, when overexpressed,
spontaneously self-assemble into particles that are antigenically indistinguishable from …

The actin cytoskeleton has been implicated in restricting diffusion of plasma membrane
components. Here, simultaneous observations of quantum dot-labelled FcɛRI motion and …

Introduction A primary focus of HIV‐1 vaccine development is the activation of B cell
receptors for naïve or precursor broadly neutralizing antibodies (bnAbs), followed by …

Depending on the stimuli they encounter, B lymphocytes engage in signaling events that
lead to immunity or tolerance. Both responses are mediated through antigen interactions …

Two-component, self-assembling nanoparticles represent a versatile platform for multivalent
presentation of viral antigens. Computational design of protein nanoparticles with differing …

Summary Crosslinking of IgE-bound FcɛRI triggers mast cell degranulation. Previous
fluorescence recovery after photobleaching (FRAP) and phosphorescent anisotropy studies …