Neutrophils in cancer: heterogeneous and multifaceted

CC Hedrick, I Malanchi - Nature Reviews Immunology, 2022 - nature.com
Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

Neutrophil diversity and plasticity in tumour progression and therapy

S Jaillon, A Ponzetta, D Di Mitri, A Santoni… - Nature Reviews …, 2020 - nature.com
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

[HTML][HTML] Tumor-associated neutrophils suppress antitumor immunity of NK cells through the PD-L1/PD-1 axis

R Sun, Y Xiong, H Liu, C Gao, L Su, J Weng… - Translational …, 2020 - Elsevier
Studies have begun to emerge showing the protumor effects of tumor-associated neutrophils
(TANs) in tumorigenesis, which may involve dysfunction of NK cells. However, the …

Loss of CXCR4 in myeloid cells enhances antitumor immunity and reduces melanoma growth through NK cell and FASL mechanisms

J Yang, A Kumar, AE Vilgelm, SC Chen, GD Ayers… - Cancer immunology …, 2018 - AACR
The chemokine receptor, CXCR4, is involved in cancer growth, invasion, and metastasis.
Several promising CXCR4 antagonists have been shown to halt tumor metastasis in …

Primary tumors limit metastasis formation through induction of IL15-mediated cross-talk between patrolling monocytes and NK cells

H Kubo, S Mensurado, N Gonçalves-Sousa… - Cancer immunology …, 2017 - AACR
Metastases are responsible for the vast majority of cancer-related deaths. Although tumor
cells can become invasive early during cancer progression, metastases formation typically …

Functional and Phenotypic Changes of Natural Killer Cells in Whole Blood during Mycobacterium tuberculosis Infection and Disease

M Garand, M Goodier, O Owolabi, S Donkor… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) is still a global health concern, especially in resource-poor countries such
as The Gambia. Defining protective immunity to TB is challenging: its pathogenesis is …

The 'danse macabre'—neutrophils the interactive partner affecting oral cancer outcomes

S Hadjigol, BA Shah, NM O'Brien-Simpson - Frontiers in Immunology, 2022 - frontiersin.org
Over the past few decades, tremendous advances in the prevention, diagnosis, and
treatment of cancer have taken place. However for head and neck cancers, including oral …

Co‐expression network analysis identified key proteins in association with hepatic metastatic colorectal cancer

W Yang, J Shi, Y Zhou, T Liu, J Li… - PROTEOMICS …, 2019 - Wiley Online Library
Purpose Intense efforts have been made in colorectal cancer (CRC) treatment in recent
decades. However, the mechanism of development and metastasis of CRC has not been …

[HTML][HTML] Intratumoral immunization by p19Arf and interferon-β gene transfer in a heterotopic mouse model of lung carcinoma

JPP Catani, RFV Medrano, A Hunger, P Del Valle… - Translational …, 2016 - Elsevier
Therapeutic strategies that act by eliciting and enhancing antitumor immunity have been
clinically validated as an effective treatment modality but may benefit from the induction of …

Cell expansion

BJ Nankervis, ME Jones - US Patent 11,624,046, 2023 - Google Patents
US11624046B2 - Cell expansion - Google Patents US11624046B2 - Cell expansion -
Google Patents Cell expansion Download PDF Info Publication number US11624046B2 …