Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases

R Castañeda, A Cáceres, SM Cruz, JA Aceituno… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The prevalence of kidney disease has increased rapidly in
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …

[PDF][PDF] Protective Effect of Ethanolic Extract of Jati Belanda (Guazuma ulmifolia L.) by Inhibiting Oxidative Stress and Inflammatory Processes in Cisplatin-induced …

W Widowati, S Prahastuti, M Hidayat… - Pakistan Veterinary …, 2022 - pvj.com.pk
The accumulation of high concentrations of cisplatin in the kidneys may cause
nephrotoxicity. Cisplatin-induced nephrotoxicity happens through the inflammation of the …

[HTML][HTML] Hepatoprotective properties of red betel (Piper crocatum Ruiz and Pav) leaves extract towards H2O2-induced HepG2 cells via anti-inflammatory, antinecrotic …

INE Lister, CN Ginting, E Girsang, ED Nataya… - Saudi Pharmaceutical …, 2020 - Elsevier
Background Prolonged exposure of free radicals, or known as reactive oxygen species
(ROS), in hepatic cells may cause oxidative stress. Without proper treatment, it can induce …

[HTML][HTML] Hepatotoxicity prevention in Acetaminophen-induced HepG2 cells by red betel (Piper crocatum Ruiz and Pav) extract from Indonesia via antioxidant, anti …

CN Ginting, INE Lister, E Girsang, W Widowati… - Heliyon, 2021 - cell.com
Acetaminophen (APAP) is a widely used analgesic, but it may cause liver injury
(hepatotoxicity) via oxidative stress that induced by N-acetyl-p-benzoquinone imine (NAPQI) …

[HTML][HTML] Quercetin prevents chronic kidney disease on mesangial cells model by regulating inflammation, oxidative stress, and TGF-β1/SMADs pathway

W Widowati, S Prahastuti, R Tjokropranoto… - PeerJ, 2022 - peerj.com
Background Chronic kidney disease (CKD) happens due to decreasing kidney function.
Inflammation and oxidative stress have been shown to result in the progression of CKD …

Antioxidant activity of TEMON (Clitoria ternatea and Citrus sp.) as an infused herbal tea

W Widowati, TL Wargasetia, TM Zakaria… - Majalah Obat …, 2022 - journal.ugm.ac.id
Many people around the world believed that herbal tea had a lot of antioxidants contained in
it, thus it was widely drunk all over the world. However, the antioxidant capacities of herbal …

[PDF][PDF] The ethanol extract of the bastard cedar (Guazuma ulmifolia L.) as antioxidants

S Prahastuti, M Hidayat, ST Hasiana, W Widowati… - …, 2020 - eprints.uad.ac.id
Guazuma ulmifolia, or commonly known as the bastard cedar, has many pharmaceutical
activities. Therefore, it is claimed as a source of various plant-based medicines. This …

Antioxidant and anti-inflammatory activity of chlorogenic acid on lead-induced fibroblast cells

E Girsang, INE Lister, CN Ginting… - Journal of Physics …, 2019 - iopscience.iop.org
Lead (Pb) can be a cause of oxidative stress, because it is a toxin found in the environment
and can have a harmful effect on the body. increased reactive oxygen species (ROS) and …

[HTML][HTML] Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7)

W Widowati, HSW Kusuma… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): Inflammation is thought to be the common pathophysiological basis for several
disorders. Corilagin is one of the major active compounds which showed broad-spectrum …

[HTML][HTML] The role of green peas protein hydrolysate in TGF/SMAD signaling to prevent renal fibrosis

M Hidayat, S Prahastuti, E Afifah, W Widowati… - Journal of King Saud …, 2022 - Elsevier
Objectives The protein of green peas (Pisum sativum) hydrolyzed by bromelain (PHGPB)
shows an effective renal fibrosis therapy by improving renal function parameters in the CKD …