Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

Ischemic stroke is the second cause of mortality and the first cause of long-term disability
constituting a serious socioeconomic burden worldwide. Approved treatments include …

Background Neonatal hypoxic–ischemic encephalopathy is an important cause of death as
well as long-term disability in survivors. Erythropoietin has been hypothesized to have …

OBJECTIVE: To determine if multiple doses of erythropoietin (Epo) administered with
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …

Restorative strategies after stroke are focused on the remodeling of cerebral endothelial
cells and brain parenchymal cells. The latter, ie, neurons, neural precursor cells and glial …

Recent laboratory findings suggest that it might be possible to promote cerebral plasticity
and neurological recovery after stroke by use of exogenous pharmacological or cell-based …

Current understanding of the mechanisms underlying neural plasticity changes after stroke
stems from experimental models as well as clinical studies and provides the foundation for …

Hypoxia is a central pathophysiological component in cancer, myocardial infarction and
ischemic stroke, which represent the most common medical conditions resulting in long-term …

Neuronal injury from ischemic stroke is aggravated by invading peripheral immune cells.
Early infiltrates of neutrophil granulocytes and T-cells influence the outcome of stroke. So far …

Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …