Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

The constant dynamic movement of synapses and their components has emerged in the last
decades as a key feature of synaptic transmission and its plasticity. Intramolecular protein …

The neurotransmitters GABA and glycine mediate fast synaptic inhibition by activating ligand-
gated chloride channels—namely, type A GABA (GABAA) and glycine receptors. Both types …

Proper developmental, neural cell-type-specific, and activity-dependent regulation of
GABAergic transmission is essential for virtually all aspects of CNS function. The number of …

Soluble oligomers of amyloid β (Aβ) play a role in the memory impairment characteristic of
Alzheimer's disease. Acting as pathogenic ligands, Aβ oligomers bind to particular synapses …

INTRODUCTION During development, brain circuits go through phases of synapse
formation, stabilization, or elimination. γ-aminobutyric acid–mediated (GABAergic) synapse …

Cellular mechanisms that regulate the interplay of synaptic excitation and inhibition are
thought to be central to the functional stability of healthy neuronal circuits. A growing body of …

Inflammation has been implicated in the progression of neurological disease, yet precisely
how inflammation affects neuronal function remains unclear. Tumor necrosis factor-α (TNFα) …

Autoimmune synaptic encephalitides are recently described human brain diseases leading
to psychiatric and neurological syndromes through inappropriate brain–autoantibody …

Repetitive transcranial magnetic stimulation (rTMS) is used as a therapeutic tool in
neurology and psychiatry. While repetitive magnetic stimulation (rMS) has been shown to …