The increasing interest of the oncology community in tumour classification and prediction of
outcome to targeted therapies has put emphasis on an improved identification of tumour …

A variety of genetic and molecular alterations underlie the development and progression of
colorectal neoplasia (CRN). Most of these cancers arise sporadically due to multiple somatic …

Background The incidence rate of colorectal cancer (CRC) is increasing among patients
below 50 years of age. The reason for this is unclear, but could have to do with the fact that …

The identification of genes that are differentially methylated in colorectal cancer (CRC) has
potential value for both diagnostic and therapeutic interventions specifically in high-risk …

Results: 2654 colonoscopies were included in the study. The mean age of the study
population was 50.5 years [standard deviation (SD) 15.9] and females represented 57.7 …

Background Colorectal (CRC) carcinogenesis through various morphological stages has
been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal …

AIM To identify the prevalence, and clinical and pathologic characteristic of colonic polyps
among Iranian patients undergoing a comprehensive colonoscopy, and determine the polyp …

According to the most recent GLOBOCAN report, Colorectal Cancer (CRC) is considered the
third most commonly diagnosed cancer and the second leading cause of cancer-related …

Materials and Methods: We collected patients' demographic data, FOBT results, and
colonoscopy pathology reports results. Statistical Analysis: Data were analyzed using the …

PURPOSE Next Generation Sequencing (NGS) is currently used to establish mutational
profiles in many multigene diseases such as colorectal cancer (CRC), which is on the rise in …