Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance

AP Johnson, N Woodford - Journal of medical …, 2013 - microbiologyresearch.org
The rapidity with which new types of antibiotic resistance can disseminate globally following
their initial emergence or recognition is exemplified by the novel carbapenemase New Delhi …

“Stormy waters ahead”: global emergence of carbapenemases

G Patel, RA Bonomo - Frontiers in microbiology, 2013 - frontiersin.org
Carbapenems, once considered the last line of defense against of serious infections with
Enterobacteriaceae, are threatened with extinction. The increasing isolation of carbapenem …

New Delhi Metallo-beta-lactamase around the world: an eReview using Google Maps

M Berrazeg, SM Diene, L Medjahed, P Parola… - …, 2014 - eurosurveillance.org
Gram-negative carbapenem-resistant bacteria, in particular those producing New Delhi
Metallo-beta-lactamase-1 (NDM-1), are a major global health problem. To inform the …

Outbreak of Carbapenem-Resistant Enterobacteriaceae Containing blaNDM-1, Ontario, Canada

S Borgia, O Lastovetska, D Richardson… - Clinical infectious …, 2012 - academic.oup.com
Abstract Background. New Delhi metallo-ß-lactamase (NDM) has emerged worldwide in
clinically relevant gram-negative bacteria. We report an outbreak of NDM-producing …

[HTML][HTML] Emergence of New Delhi metallo-β-lactamase type 1-producing Enterobacteriaceae and non-Enterobacteriaceae: global case detection and bacterial …

G Bushnell, F Mitrani-Gold, LM Mundy - International journal of infectious …, 2013 - Elsevier
OBJECTIVE: A systematic review of the literature was conducted to summarize the
descriptive and molecular epidemiology of human cases and surveillance reports with New …

Treatment options for New Delhi metallo-beta-lactamase-harboring enterobacteriaceae

BA Rogers, HE Sidjabat, A Silvey… - Microbial drug …, 2013 - liebertpub.com
The New Delhi metallo-β-lactamase gene (bla NDM-1) has emerged as a worldwide
concern among isolates of Enterobacteriaceae. Its epidemiology is been strongly associated …

Zinc ion-induced conformational changes in new Delphi metallo-β-lactamase 1 probed by molecular dynamics simulations and umbrella sampling

J Chen, J Wang, W Zhu - Physical Chemistry Chemical Physics, 2017 - pubs.rsc.org
The hydrolysis of a β-lactam core ring caused by new Delphi metallo-β-lactamase 1 (NDM-
1) with the help of two zinc cofactors induces significant resistance toward β-lactam …

NDM carbapenemases in the United Kingdom: an analysis of the first 250 cases

A Jain, KL Hopkins, J Turton, M Doumith… - Journal of …, 2014 - academic.oup.com
Objectives Gram-negative bacteria with diverse carbapenemases, including New Delhi
metallo-β-lactamase (NDM) enzymes, have been increasingly recorded in the UK since …

[HTML][HTML] Emergence of NDM-1-producing Enterobacteriaceae in Porto Alegre, Brazil

FP Rozales, VB Ribeiro, CM Magagnin… - International Journal of …, 2014 - Elsevier
Objectives To evaluate the emergence of New Delhi metallo-β-lactamase 1 (NDM-1)-
producing Enterobacteriaceae isolates in Brazil. Methods From April to October 2013 …

New Delhi metallo-β-lactamase-mediated carbapenem resistance: origin, diagnosis, treatment and public health concern

WJ Wei, HF Yang, Y Ye, JB Li - Chinese medical journal, 2015 - mednexus.org
Objective: To review the origin, diagnosis, treatment and public health concern of New Delhi
metallo-β-lactamase (NDM)-producing bacteria. Data Sources: We searched database for …