[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

History and update on host defense against vaginal candidiasis

PL Fidel Jr - American journal of reproductive immunology, 2007 - Wiley Online Library
Vulvovaginal candidiasis (VVC), caused by Candida albicans, remains a significant problem
in women of childbearing age. While cell‐mediated immunity is considered the predominant …

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

HR Conti, F Shen, N Nayyar, E Stocum… - Journal of Experimental …, 2009 - rupress.org
The commensal fungus Candida albicans causes oropharyngeal candidiasis (OPC; thrush)
in settings of immunodeficiency. Although disseminated, vaginal, and oral candidiasis are all …

An Intravaginal Live Candida Challenge in Humans Leads to New Hypotheses for the Immunopathogenesis of Vulvovaginal Candidiasis

PL Fidel Jr, M Barousse, T Espinosa… - Infection and …, 2004 - Am Soc Microbiol
Acute and recurrent vulvovaginal candidiasis (VVC) remains a significant problem in women
of childbearing age. While clinical studies of women with recurrent VVC (RVVC) and animal …

T cell receptor-deficient T cell compositions

CL Sentman - US Patent 9,181,527, 2015 - Google Patents
The invention is directed to modified T cells, methods of making and using isolated, modified
T cells, and methods of using these isolated, modified T cells to address diseases and …

Novel mechanism behind the immunopathogenesis of vulvovaginal candidiasis:“neutrophil anergy”

J Yano, BM Peters, MC Noverr… - Infection and immunity, 2018 - Am Soc Microbiol
For over 3 decades, investigators have studied the pathogenesis of vulvovaginal candidiasis
(VVC) and recurrent VVC (RVVC) through clinical studies and animal models. While there …

Candida Vaginitis: When Opportunism Knocks, the Host Responds

BM Peters, J Yano, MC Noverr, PL Fidel Jr - PLoS pathogens, 2014 - journals.plos.org
Candida albicans, an opportunistic polymorphic fungus and resident of the normal vaginal
microbiota, is the leading causative agent of vulvovaginal candidiasis (VVC) and presents …

IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis

A De Luca, A Carvalho, C Cunha, RG Iannitti… - PLoS …, 2013 - journals.plos.org
The ability to tolerate Candida albicans, a human commensal of the gastrointestinal tract
and vagina, implicates that host defense mechanisms of resistance and tolerance cooperate …

Immunity in vaginal candidiasis

PL Fidel Jr - Current opinion in infectious diseases, 2005 - journals.lww.com
Instead of vulvovaginal candidiasis being caused by defective or dysfunctional CD4+ T
helper 1-type cell-mediated immune reactivity, data suggest that symptomatic vulvovaginal …

Cytokines in the host response to Candida vaginitis: Identifying a role for non-classical immune mediators, S100 alarmins

J Yano, MC Noverr, PL Fidel Jr - Cytokine, 2012 - Elsevier
Vulvovaginal candidiasis (VVC), caused by Candida albicans, affects a significant number of
women during their reproductive years. More than two decades of research have been …