Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
[HTML][HTML] Common pathogenetic mechanisms underlying aging and tumor and means of interventions
W Shen, J He, T Hou, J Si, S Chen - Aging and disease, 2022 - ncbi.nlm.nih.gov
Recently, there has been an increase in the incidence of malignant tumors among the older
population. Moreover, there is an association between aging and cancer. During the …
population. Moreover, there is an association between aging and cancer. During the …
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice
XL Liu, YC Zhao, HY Zhu, M Wu, YN Zheng, M Yang… - Food & function, 2021 - pubs.rsc.org
Aging and aging-related metabolic complications are global problems that seriously
threaten public health. Taxifolin (TAX) is a novel health food and has been widely proved to …
threaten public health. Taxifolin (TAX) is a novel health food and has been widely proved to …
Neuroprotective effects of Ellagic acid against acrylamide-induced neurotoxicity in rats
M Goudarzi, MA Mombeini, I Fatemi… - Neurological …, 2019 - Taylor & Francis
Acrylamide (ACR) is an environmental contaminant and a well-known neurotoxin. Ellagic
acid (EA), a natural plant polyphenol, has shown a variety of beneficial effects. The present …
acid (EA), a natural plant polyphenol, has shown a variety of beneficial effects. The present …
Phlorizin exerts potent effects against aging induced by D-galactose in mice and PC12 cells
Y Liu, Y Liu, Y Guo, L Xu, H Wang - Food & Function, 2021 - pubs.rsc.org
Phlorizin is the main active ingredient of apple peel and has potential utilization value. Some
recent studies have suggested that phlorizin may have antioxidant capacity and protect the …
recent studies have suggested that phlorizin may have antioxidant capacity and protect the …
[HTML][HTML] A Pectic Polysaccharide from Codonopsis pilosula Alleviates Inflammatory Response and Oxidative Stress of Aging Mice via Modulating Intestinal Microbiota …
Y Zou, H Yan, C Li, F Wen, X Jize, C Zhang, S Liu… - Antioxidants, 2023 - mdpi.com
Aging is a biological process that leads to the progressive deterioration and loss of
physiological functions in the human body and results in an increase in morbidity and …
physiological functions in the human body and results in an increase in morbidity and …
[HTML][HTML] Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway
Slowing down age-related neurocognitive impairment has been a challenge. We evaluated
the therapeutic effects of metformin in d-galactose-induced aging. Additionally, we studied …
the therapeutic effects of metformin in d-galactose-induced aging. Additionally, we studied …
Ziziphus jujuba (Rhamnaceae) Alleviates Working Memory Impairment and Restores Neurochemical Alterations in the Prefrontal Cortex of D‐Galactose‐Treated Rats
AK Kandeda, D Nguedia, ER Ayissi… - Evidence‐Based …, 2021 - Wiley Online Library
Alzheimer's disease is a progressive cognitive dysfunction. However, pharmacological
treatments are symptomatic and have many side effects, opening the opportunity to …
treatments are symptomatic and have many side effects, opening the opportunity to …
[HTML][HTML] Antioxidant Effect of Soymilk Fermented by Lactobacillus plantarum HFY01 on D-Galactose-Induced Premature Aging Mouse Model
C Li, Y Fan, S Li, X Zhou, KY Park, X Zhao… - Frontiers in Nutrition, 2021 - frontiersin.org
The antioxidant effect of soymilk fermented by Lactobacillus plantarum HFY01 (screened
from yak yogurt) was investigated on mice with premature aging induced by D-galactose. In …
from yak yogurt) was investigated on mice with premature aging induced by D-galactose. In …
Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis
Diabetes mellitus (DM) is a metabolic disease that activates several molecular pathways
involved in neurodegenerative disorders. Metformin, an anti-hyperglycemic drug used for …
involved in neurodegenerative disorders. Metformin, an anti-hyperglycemic drug used for …