Annexin A1 and glucocorticoids as effectors of the resolution of inflammation
M Perretti, F D'acquisto - Nature Reviews Immunology, 2009 - nature.com
Glucocorticoids are widely used for the management of inflammatory diseases. Their clinical
application stems from our understanding of the inhibitory effect of the corticosteroid …
application stems from our understanding of the inhibitory effect of the corticosteroid …
Annexins: linking Ca2+ signalling to membrane dynamics
Eukaryotic cells contain various Ca2+-effector proteins that mediate cellular responses to
changes in intracellular Ca2+ levels. A unique class of these proteins—annexins—can bind …
changes in intracellular Ca2+ levels. A unique class of these proteins—annexins—can bind …
International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family
DY Richard, F Boulay, JM Wang, C Dahlgren… - Pharmacological …, 2009 - ASPET
Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …
Annexin A1: uncovering the many talents of an old protein
MH Sheikh, E Solito - International journal of molecular sciences, 2018 - mdpi.com
Annexin A1 (ANXA1) has long been classed as an anti-inflammatory protein due to its
control over leukocyte-mediated immune responses. However, it is now recognized that …
control over leukocyte-mediated immune responses. However, it is now recognized that …
Annexins–unique membrane binding proteins with diverse functions
U Rescher, V Gerke - Journal of cell science, 2004 - journals.biologists.com
Annexins are a well-known multigene family of Ca2+-regulated phospholipid-binding and
membrane-binding proteins. Recent work employing annexin-knockdown or-knockout …
membrane-binding proteins. Recent work employing annexin-knockdown or-knockout …
Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses
I Migeotte, D Communi, M Parmentier - Cytokine & growth factor reviews, 2006 - Elsevier
The formyl peptide receptor (FPR) family is involved in host defence against pathogens, but
also in sensing internal molecules that may constitute signals of cellular dysfunction. It …
also in sensing internal molecules that may constitute signals of cellular dysfunction. It …
The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo
Lipoxins (LXs) and aspirin-triggered LX (ATL) are trihydroxytetraene-containing eicosanoids
generated from arachidonic acid that are distinct in structure, formation, and function from …
generated from arachidonic acid that are distinct in structure, formation, and function from …
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation
N Dufton, R Hannon, V Brancaleone, J Dalli… - The Journal of …, 2010 - journals.aai.org
The human formyl-peptide receptor (FPR)-2 is a G protein-coupled receptor that transduces
signals from lipoxin A 4, annexin A1, and serum amyloid A (SAA) to regulate inflammation. In …
signals from lipoxin A 4, annexin A1, and serum amyloid A (SAA) to regulate inflammation. In …
Annexin 1: the new face of an old molecule
LHK Lim, S Pervaiz - The FASEB Journal, 2007 - Wiley Online Library
The annexin superfamily consists of 13 calcium or calcium and phospholipid binding
proteins with a significant degree of biological and structural homology (40–60%). First …
proteins with a significant degree of biological and structural homology (40–60%). First …
Effects of low-dose aspirin on acute inflammatory responses in humans
T Morris, M Stables, A Hobbs, P de Souza… - The Journal of …, 2009 - journals.aai.org
Aspirin is a unique nonsteroidal anti-inflammatory drug; at high doses (aspirin high, 1g), it is
anti-inflammatory stemming from the inhibition of cyclooxygenase and proinflammatory …
anti-inflammatory stemming from the inhibition of cyclooxygenase and proinflammatory …