Importance Cefazolin is the preoperative antibiotic of choice because it is safer and more
efficacious than second-line alternatives. Surgical patients labeled as having penicillin …

Background Surgical site infection following joint replacement surgery is still a significant
complication, resulting in repeated surgery, prolonged antibiotic therapy, extended …

β-lactam antibiotics (BL) are the first-choice antibiotic therapy for numerous infections,
among them, penicillin is the most recognized. 1, 2 Moreover, beta-lactams are the most …

Background Patients with a patient-reported penicillin allergy may be at greater risk for
postoperative prosthetic joint infection (PJI) after total joint arthroplasty of the hip, knee, or …

Although there are numerous nonpatient-related factors that may help reduce infection risk,
the proper use of prophylactic antibiotics is most responsible for reducing infection. The role …

Background Most patients who report a penicillin allergy can tolerate cefazolin, the preferred
prophylaxis in a total joint arthroplasty (TJA). Regardless, patients with a reported penicillin …

Background The aim of the present study was to compare causative bacteria and their
antibiotic resistance profiles in patients developing a periprosthetic joint infection (PJI) …

Primary total hip arthroplasty (THA) procedures continue to increase. On the basis of data
from 2000 to 2014, the frequency of THA in the US is projected to grow to 635,000 …

Bone flap infection is often experienced as a complication of cranioplasty. The aim of this
study was to investigate predictors of graft infection, including patient-specific and surgery …

Background The purpose of this study is to determine if the number and types of patient-
reported drug allergies are associated with prosthetic joint infection (PJI) and functional …