The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications

Z Hu, D Ma - Cancer medicine, 2018 - Wiley Online Library
Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …

[HTML][HTML] Therapeutic effects of date fruits (Phoenix dactylifera) in the prevention of diseases via modulation of anti-inflammatory, anti-oxidant and anti-tumour activity

AH Rahmani, SM Aly, H Ali, AY Babiker… - International journal of …, 2014 - ncbi.nlm.nih.gov
The current mode of treatment of various diseases based on synthetic drugs is expensive,
alters genetic and metabolic pathways and also shows adverse side effects. Thus, safe and …

Therapeutic implications of black seed and its constituent thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways

AH Rahmani, MA Alzohairy, MA Khan… - Evidence‐Based …, 2014 - Wiley Online Library
The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …

PTEN and gynecological cancers

C Nero, F Ciccarone, A Pietragalla, G Scambia - Cancers, 2019 - mdpi.com
PTEN is a tumour suppressor gene, and its loss of function is frequently observed in both
heritable and sporadic cancers. It is involved in a great variety of biological processes …

MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma

B Otoukesh, M Abbasi, HL Gorgani, H Farahini… - Cancer cell …, 2020 - Springer
MicroRNAs (miRNAs) involved in key signaling pathways and aggressive phenotypes of
osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 …

[HTML][HTML] Downregulation of microRNA-147 inhibits cell proliferation and increases the chemosensitivity of gastric cancer cells to 5-fluorouracil by directly targeting …

J Shen, W Niu, H Zhang, M Jun, H Zhang - Oncology Research, 2018 - ncbi.nlm.nih.gov
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-
related deaths worldwide. This study aimed to investigate the expression patterns, biological …

miR-21 inhibitor suppresses cell proliferation and colony formation through regulating the PTEN/AKT pathway and improves paclitaxel sensitivity in cervical cancer …

G Du, D Cao, L Meng - Molecular medicine reports, 2017 - spandidos-publications.com
The present study aimed to investigate the role and the molecular mechanisms underlying
the effects of microRNA-21 (miR-21) on the proliferation, apoptosis and colony formation of …

MicroRNA-22 is downregulated in clear cell renal cell carcinoma, and inhibits cell growth, migration and invasion by targeting PTEN

W Fan, J Huang, H Xiao… - Molecular medicine …, 2016 - spandidos-publications.com
Abstract MicroRNA (miR)-22 has previously been reported to be frequently downregulated
in certain types of cancer. The present study examined the expression and effects of miR-22 …

[HTML][HTML] Distribution of HPV genotypes and involvement of risk factors in cervical lesions and invasive cervical cancer: a study in an Indian population

S Srivastava, UP Shahi, A Dibya, S Gupta… - International journal of …, 2014 - ncbi.nlm.nih.gov
Human papilloma virus (HPV) is considered as the main sexually transmitted etiological
agent for the cause and progression of preneoplastic cervical lesions to cervical cancer. This …

Epidermal growth factor receptor pathway mutation and expression profiles in cervical squamous cell carcinoma: therapeutic implications

S Bumrungthai, K Munjal, S Nandekar… - Journal of Translational …, 2015 - Springer
Background Cervical squamous cell carcinoma (CSCC) is a major cause of female mortality
worldwide. This study has examined epidermal growth factor receptor (EGFR) pathway …