Molecular principles of metastasis: a hallmark of cancer revisited
Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …
Cancer-associated fibroblasts and tumor-associated macrophages in cancer and cancer immunotherapy
Our understanding of the tumor microenvironment (TME), including the interplay between
tumor cells, stromal cells, immune cells, and extracellular matrix components, is mandatory …
tumor cells, stromal cells, immune cells, and extracellular matrix components, is mandatory …
Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development
AV Samarelli, V Masciale, B Aramini, GP Coló… - International journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of …
disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of …
Cancer: a mirrored room between tumor bulk and tumor microenvironment
P Hernández-Camarero, E López-Ruiz… - Journal of Experimental …, 2021 - Springer
It has been well documented that the tumor microenvironment (TME) plays a key role in the
promotion of drug resistance, the support of tumor progression, invasiveness, metastasis …
promotion of drug resistance, the support of tumor progression, invasiveness, metastasis …
NETosis: sculpting tumor metastasis and immunotherapy
Y Hu, H Wang, Y Liu - Immunological Reviews, 2024 - Wiley Online Library
The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …
death modality of neutrophils, which was first observed as an immune response against …
Exosome-mediated tumor metastasis: Biology, molecular targets and Immuno-therapeutic options
R Moshrefiravasjani, A Kamrani, N Nazari… - … -Research and Practice, 2024 - Elsevier
Small extracellular vesicles called exosomes play a crucial part in promoting intercellular
communication. They act as intermediaries for the exchange of bioactive chemicals between …
communication. They act as intermediaries for the exchange of bioactive chemicals between …
Natural killer cells in cancer and cancer immunotherapy
The detection and killing of neoplastic cells require coordination of a variety of antitumor
effector cells. Natural killer (NK) cells of the innate immune system are at the forefront of the …
effector cells. Natural killer (NK) cells of the innate immune system are at the forefront of the …
Molecular principles of tissue invasion and metastasis
D Sulekha Suresh… - American Journal of …, 2023 - journals.physiology.org
Cancer-associated metastasis is the primary cause of morbidity and mortality. Yet, its
underlying biological mechanism remains poorly understood. Efforts to prevent or delay …
underlying biological mechanism remains poorly understood. Efforts to prevent or delay …
Clinical implications of exosomes: targeted drug delivery for cancer treatment
AE Massey, S Malik, M Sikander, KA Doxtater… - International Journal of …, 2021 - mdpi.com
Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to
their composition, significant research has been conducted to transform these particles into …
their composition, significant research has been conducted to transform these particles into …
Cancer stem cells and circulatory tumor cells promote breast cancer metastasis
Breast cancer (BC) is a highly metastatic, pathological cancer that significantly affects
women worldwide. The mortality rate of BC is related to its heterogeneity, aggressive …
women worldwide. The mortality rate of BC is related to its heterogeneity, aggressive …