Ketamine, a non-competitive antagonist of N-methyl-D-aspartate (NMDA) receptor, displays
a fast antidepressant activity in treatment-resistant depression and in rodent models of …

IMPLICATIONS: Ketamine can be used safely in neurologically impaired patients under
conditions of controlled ventilation, coadministration of a γ-aminobutyric acid receptor …

Rationale Behavioural antidepressant-like effects of ketamine have been reported in the
forced swimming test (FST). The mechanisms mediating such effects are unknown …

Beyond direct synaptic communication, neurons are able to talk to each other without
making synapses. They are able to send chemical messages by means of diffusion to target …

Ketamine, a dissociative anesthetic agent, appears to have rapid antidepressant effects at
sub-anesthetic doses in clinically depressed patients. Although promising, these results …

Background The use of ketamine for depression has increased rapidly in the past decades.
Ketamine is often prescribed as an add-on to other drugs used in psychiatric patients, but …

This study investigated the effectiveness of ketamine, a noncompetitive N-methyl-d-
aspartate (NMDA) receptor antagonist, in alleviating the enhanced anxiety and fear …

Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phenolic compound present in several
plants with claimed beneficial effects in prevention and treatment of disorders linked to …

Repurposing ketamine in the therapy of depression could well represent a breakthrough in
understanding the etiology of depression. Ketamine was originally used as an anesthetic …

Ketamine, a noncompetitive antagonist of the N-methyl-d-aspartate type of glutamate
receptors, was reported to induce neuronal cell death when administered to produce …