Abstract Background The Infectious Diseases Society of America is committed to providing
up-to-date guidance on the treatment of antimicrobial-resistant infections. This guidance …

Abstract The Infectious Diseases Society of America (IDSA) is committed to providing up-to-
date guidance on the treatment of antimicrobial-resistant infections. A previous guidance …

Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …

Antimicrobial resistance has become one of the greatest threats to public health, with rising
resistance to carbapenems being a particular concern due to the lack of effective and safe …

The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …

The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

Stenotrophomonas maltophilia is a Gram-negative, biofilm-forming bacterium. Although
generally regarded as an organism of low virulence, S. maltophilia is an emerging multi …

Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in
the past few years, posing great challenges to human health. The plasmid-mediated …

Intrathecal administration of anti-infectives is indicated in central nervous system infections
by multiresistant pathogens when drugs that can reach adequate cerebrospinal fluid (CSF) …

Carbapenem-resistant Enterobacteriaceae (CRE) infections are prevalent worldwide; they
have few effective treatments and this jeopardizes public health. Clinicians often use …