Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic
signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors …

Eight G protein‐coupled P2Y receptor subtypes respond to extracellular adenine and uracil
mononucleotides and dinucleotides. P2Y receptors belong to the δ group of rhodopsin‐like …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

Nucleotides and cysteinyl‐leukotrienes (CysLTs) are unrelated signaling molecules
inducing multiple effects through separate G‐protein‐coupled receptors: the P2Y and the …

Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …

Microglia play an important role as immune cells in the central nervous system (CNS).
Microglia are activated in threatened physiological homeostasis, including CNS trauma …

phoprotein (VASP) assay, which specifically explores the function of platelet P2Y12. These
patients were randomized to undergo VASP-guided additional loading doses of 600 mg …

Deciphering the mechanisms regulating the generation of new neurons and new
oligodendrocytes, the myelinating cells of the central nervous system, is of paramount …