Living tissues are active, multifunctional materials capable of generating, sensing,
withstanding and responding to mechanical stress. These capabilities enable tissues to …

The F-type lectin (FTL) family is one of the most recent to be identified and structurally
characterized. Members of the FTL family are characterized by a fucose recognition domain …

Many biological processes involve the collective generation and transmission of mechanical
stresses across cell monolayers. In these processes, the monolayer undergoes lateral …

Cellular functions, such as division and migration, require cells to undergo robust shape
changes. Through their contractility machinery, cells also sense, respond, and adapt to their …

Cellular traction force microscopy (TFM) requires knowledge of the mechanical properties of
the substratum where the cells adhere to calculate cell-generated forces from …

Intracellular bacterial infections alter the normal functionality of human host cells and
tissues. Infection can also modify the mechanical properties of host cells, altering the …

MFSD8 is a transmembrane protein that has been reported to transport chloride ions across
the lysosomal membrane. Mutations in MFSD8 are associated with a subtype of Batten …

During development, coordinated cell shape changes alter tissue shape. In the Drosophila
ventral furrow and other epithelia, apical constriction of hundreds of epithelial cells folds the …

F-type lectins (FTLs) are characterized by a fucose recognition domain (F-type lectin
domain; FTLD) that displays a novel jellyroll fold (“F-type” fold) and unique carbohydrate …

The social amoeba Dictyostelium discoideum switches between the phase of solitary growth
and social fruitification depending on nutrient availability. Under non-nutrient conditions …