Tuberculosis (TB) remains one of the deadliest infectious diseases in the world and every 20
seconds a person dies from TB. An important attribute of human TB is induction of a …

Infection with H. pylori induces chronic gastric inflammation, progressing to peptic ulcer and
stomach adenocarcinoma. Macrophages function as innate immune cells and play a vital …

Despite advancements in understanding the pathophysiology of Multiple Myeloma (MM), the
cause of rapid progressing disease in a subset of patients is still unclear. MM's progression …

Macrophages (MФ) are an essential immune cell for defense and repair that travel to
different tissues and adapt based on local stimuli. A critical factor that may govern their …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that
replicates inside human alveolar macrophages. This disease causes significant morbidity …

Multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) poses significant challenges to
global tuberculosis (TB) control efforts. Host-directed therapies (HDTs) offer a novel …

Tuberculosis is the leading cause of death due to an infectious disease worldwide. Innate
lymphoid type 3 cells (ILC3s) mediate early protection during Mycobacterium tuberculosis …

The Mycobacterium tuberculosis (MTB) infection causes tuberculosis (TB) and has been a
long-standing public-health threat. It is urgent that we discover novel antitubercular agents to …

Host-directed therapies aiming to strengthen the body's immune system, represent an
underexplored opportunity to improve treatment of tuberculosis (TB). We have previously …

Tuberculosis is a leading cause of death in mankind due to infectious agents, and
Mycobacterium tuberculosis (Mtb) infects and survives in macrophages (MФs). Although …