Abstract Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of
haem, is primarily considered an antioxidant, and has long been overlooked by …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological
processes: oxygen transport and storage, electron transfer, drug and steroid metabolism …

As the host defense response to various injuries and pathogens in the body, inflammation
can remove damaged cells and pathogens in the host organism and protect the body …

Mesenchymal stem cells (MSCs) protect tissues against cell death induced by
ischemia/reperfusion insults. This therapeutic effect seems to be controlled by physiological …

The stress-inducible protein heme oxygenase-1 provides protection against oxidative stress.
The anti-inflammatory properties of heme oxygenase-1 may serve as a basis for this …

Stressed mammalian cells up-regulate heme oxygenase 1 (Hmox1; EC 1.14. 99.3), which
catabolizes heme to biliverdin, carbon monoxide, and free iron. To assess the potential role …

Accumulating evidence suggests that oxidative stress plays a central role in the
pathogenesis of many pulmonary diseases including adult respiratory distress syndrome …

The mechanisms underlying the action of the potent anti-inflammatory interleukin-10 (IL-10)
are poorly understood. Here we show that, in murine macrophages, IL-10 induces …

Heme oxygenase 1 (HO-1) inhibits apoptosis by regulating cellular prooxidant iron. We now
show that there is an additional mechanism by which HO-1 inhibits apoptosis, namely by …