AMP-activated protein kinase—an energy sensor that regulates all aspects of cell function

DG Hardie - Genes & development, 2011 - genesdev.cshlp.org
AMP-activated protein kinase (AMPK) is a sensor of energy status that maintains cellular
energy homeostasis. It arose very early during eukaryotic evolution, and its ancestral role …

Osmotic stress signaling and osmoadaptation in yeasts

S Hohmann - Microbiology and molecular biology reviews, 2002 - Am Soc Microbiol
The ability to adapt to altered availability of free water is a fundamental property of living
cells. The principles underlying osmoadaptation are well conserved. The yeast …

Deciphering eukaryotic gene-regulatory logic with 100 million random promoters

CG de Boer, ED Vaishnav, R Sadeh, EL Abeyta… - Nature …, 2020 - nature.com
How transcription factors (TFs) interpret cis-regulatory DNA sequence to control gene
expression remains unclear, largely because past studies using native and engineered …

Sugar sensing and signaling in plants

F Rolland, B Moore, J Sheen - The plant cell, 2002 - academic.oup.com
In addition to their essential roles as substrates in carbon and energy metabolism and in
polymer biosynthesis, sugars have important hormone-like functions as primary messengers …

[HTML][HTML] SNF1/AMPK pathways in yeast

K Hedbacker, M Carlson - Frontiers in bioscience: a journal and …, 2008 - ncbi.nlm.nih.gov
The SNF1/AMPK family of protein kinases is highly conserved in eukaryotes and is required
for energy homeostasis in mammals, plants, and fungi. SNF1 protein kinase was initially …

How Saccharomyces Responds to Nutrients

S Zaman, SI Lippman, X Zhao… - Annual review of …, 2008 - annualreviews.org
Yeast cells sense the amount and quality of external nutrients through multiple
interconnected signaling networks, which allow them to adjust their metabolism …

Modular organization of cellular networks

AW Rives, T Galitski - … of the national Academy of sciences, 2003 - National Acad Sciences
We investigated the organization of interacting proteins and protein complexes into networks
of modules. A network-clustering method was developed to identify modules. This method of …

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

SP Hong, FC Leiper, A Woods… - Proceedings of the …, 2003 - National Acad Sciences
The Snf1/AMP-activated protein kinase (AMPK) family plays fundamental roles in cellular
responses to metabolic stress in eukaryotes. In humans, AMPK regulates lipid and glucose …

The regulation of filamentous growth in yeast

PJ Cullen, GF Sprague Jr - Genetics, 2012 - academic.oup.com
Filamentous growth is a nutrient-regulated growth response that occurs in many fungal
species. In pathogens, filamentous growth is critical for host–cell attachment, invasion into …

Flocculation in Saccharomyces cerevisiae: a review

EV Soares - Journal of applied microbiology, 2011 - academic.oup.com
The present work reviews and critically discusses the aspects that influence yeast
flocculation, namely the chemical characteristics of the medium (pH and the presence of …