Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

Biodegradable polymers have been widely used and have greatly promoted the
development of biomedical fields because of their biocompatibility and biodegradability. The …

Biological materials found in living organisms, many of which are proteins, feature a
complex hierarchical organization. Type I collagen, a fibrous structural protein ubiquitous in …

Tissue engineering aims to improve the function of diseased or damaged organs by creating
biological substitutes. To fabricate a functional tissue, the engineered construct should …

Ligaments and tendons are fibrous tissues with poor vascularity and limited regeneration
capacity. Currently, a ligament/tendon injury often require a surgical procedure using auto-or …

Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a
significant role in TL tissue repair, whether the treatment relies on tissue engineering …

Non-woven nanofibrous scaffolds have been developed for tendon graft application by
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …

Articular cartilage is an avascular connective tissue with a slow healing rate. Tissue
engineering scaffolds can provide appropriate condition to stimulate the natural healing …

An ideal scaffold that provides a combination of suitable mechanical properties along with
biological signals is required for successful ligament/tendon regeneration in mesenchymal …

Tissue engineering scaffolds should ideally mimic the natural ECM in structure and function.
Electrospun nanofibrous scaffolds are easily fabricated and possess a biomimetic …