The role of miRNAs in cancer: from pathogenesis to therapeutic implications

M Seven, OF Karatas, MB Duz, M Ozen - Future oncology, 2014 - Taylor & Francis
Cancer is still one of the dominating causes of deaths worldwide, although there have been
important enhancements for detection and diagnosis of cancer recently. miRNAs are shown …

miR-141 is a key regulator of renal cell carcinoma proliferation and metastasis by controlling EphA2 expression

X Chen, X Wang, A Ruan, W Han, Y Zhao, X Lu… - Clinical cancer …, 2014 - AACR
Abstract Purpose: Although microRNAs (miRNA) have been revealed as crucial modulators
of tumorigenesis, our understanding of their roles in renal cell carcinoma (RCC) is limited …

MicroRNAs and altered metabolism of clear cell renal cell carcinoma: Potential role as aerobic glycolysis biomarkers

M Morais, F Dias, AL Teixeira, R Medeiros - Biochimica et Biophysica Acta …, 2017 - Elsevier
Abstract Background Warburg Effect is a metabolic switch that occurs in most of cancer cells
but its advantages are not fully understood. This switch is known to happen in renal cell …

Extracellular vesicles from human liver stem cells inhibit renal cancer stem cell‐derived tumor growth in vitro and in vivo

A Brossa, V Fonsato, C Grange, S Tritta… - … Journal of Cancer, 2020 - Wiley Online Library
Cancer stem cells (CSCs) are considered as responsible for initiation, maintenance and
recurrence of solid tumors, thus representing the key for tumor eradication. The antitumor …

MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma

Y Li, B Guan, J Liu, Z Zhang, S He, Y Zhan, B Su… - …, 2019 - thelancet.com
Background Metastasis is the primary cause of tumor death in renal cell carcinoma (RCC).
Improved diagnostic markers of metastasis are critically needed for RCC. MicoRNAs are …

Cooperative effect of miR-141-3p and miR-145-5p in the regulation of targets in clear cell renal cell carcinoma

J Liep, E Kilic, HA Meyer, J Busch, K Jung, A Rabien - PloS one, 2016 - journals.plos.org
Background Due to the poor prognosis for advanced renal cell carcinoma (RCC), there is an
urgent need for new therapeutic targets and for prognostic markers to identify high risk …

Prognostic value of meta-signature miRNAs in renal cell carcinoma: an integrated miRNA expression profiling analysis

K Tang, H Xu - Scientific reports, 2015 - nature.com
To identify a robust panel of microRNA (miRNA) signatures that can distinguish renal cell
carcinoma (RCC) from normal kidney using miRNA expression levels. We performed a …

[HTML][HTML] miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1

H Butz, PM Szabó, HWZ Khella, R Nofech-Mozes… - Oncotarget, 2015 - ncbi.nlm.nih.gov
miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell
carcinoma aggressive behaviour by targeting CAV1 and FLOT1 - PMC Back to Top Skip to …

[HTML][HTML] Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma

F Dias, AL Teixeira, M Ferreira, B Adem, N Bastos… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Renal cell carcinoma (RCC) represents a challenge for clinicians since the nonexistence of
screening and monitoring tests contributes to the fact that one-third of patients are …

Targeted next‐generation sequencing and non‐coding RNA expression analysis of clear cell papillary renal cell carcinoma suggests distinct pathological …

CH Lawrie, E Larrea, G Larrinaga… - The Journal of …, 2014 - Wiley Online Library
Clear cell tubulopapillary renal cell carcinoma (CCPRCC) is a recently described rare renal
malignancy that displays characteristic gross, microscopic and immunohistochemical …