Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …
Genetic engineering of microalgae for enhanced lipid production
CF Muñoz, C Südfeld, MIS Naduthodi… - Biotechnology …, 2021 - Elsevier
Microalgae have the potential to become microbial cell factories for lipid production. Their
ability to convert sunlight and CO 2 into valuable lipid compounds has attracted interest from …
ability to convert sunlight and CO 2 into valuable lipid compounds has attracted interest from …
Real-time bioelectronic sensing of environmental contaminants
Real-time chemical sensing is crucial for applications in environmental and health
monitoring. Biosensors can detect a variety of molecules through genetic circuits that use …
monitoring. Biosensors can detect a variety of molecules through genetic circuits that use …
Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism
Microbial factories have been engineered to produce lipids from carbohydrate feedstocks for
production of biofuels and oleochemicals. However, even the best yields obtained to date …
production of biofuels and oleochemicals. However, even the best yields obtained to date …
[HTML][HTML] Flavin-based electron bifurcation, ferredoxin, flavodoxin, and anaerobic respiration with protons (Ech) or NAD+ (Rnf) as electron acceptors: a historical review
W Buckel, RK Thauer - Frontiers in microbiology, 2018 - frontiersin.org
Flavin-based electron bifurcation is a newly discovered mechanism, by which a hydride
electron pair from NAD (P) H, coenzyme F 420 H 2, H 2, or formate is split by flavoproteins …
electron pair from NAD (P) H, coenzyme F 420 H 2, H 2, or formate is split by flavoproteins …
[HTML][HTML] Review of NAD (P) H-dependent oxidoreductases: Properties, engineering and application
Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …
[HTML][HTML] Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation
W Buckel, RK Thauer - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2013 - Elsevier
The review describes four flavin-containing cytoplasmatic multienzyme complexes from
anaerobic bacteria and archaea that catalyze the reduction of the low potential ferredoxin by …
anaerobic bacteria and archaea that catalyze the reduction of the low potential ferredoxin by …
[HTML][HTML] NADPH-generating systems in bacteria and archaea
SK Spaans, RA Weusthuis, J Van Der Oost… - Frontiers in …, 2015 - frontiersin.org
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …
donor in all organisms. It provides the reducing power that drives numerous anabolic …
Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
C Ubaida-Mohien, A Lyashkov, M Gonzalez-Freire… - Elife, 2019 - elifesciences.org
A decline of skeletal muscle strength with aging is a primary cause of mobility loss and frailty
in older persons, but the molecular mechanisms of such decline are not understood. Here …
in older persons, but the molecular mechanisms of such decline are not understood. Here …
[HTML][HTML] Reserve flux capacity in the pentose phosphate pathway enables Escherichia coli's rapid response to oxidative stress
To counteract oxidative stress and reactive oxygen species (ROS), bacteria evolved various
mechanisms, primarily reducing ROS through antioxidant systems that utilize cofactor …
mechanisms, primarily reducing ROS through antioxidant systems that utilize cofactor …