Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators
BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …
dynamically adjust its functional state in response to changes in the environment. Altered …
Challenges and strategies faced in the electrochemical biosensing analysis of neurochemicals in vivo: A review
J Chen, X Ding, D Zhang - Talanta, 2024 - Elsevier
Our brain is an intricate neuromodulatory network, and various neurochemicals, including
neurotransmitters, neuromodulators, gases, ions, and energy metabolites, play important …
neurotransmitters, neuromodulators, gases, ions, and energy metabolites, play important …
The development of an implantable deep brain stimulation device with simultaneous chronic electrophysiological recording and stimulation in humans
Deep brain stimulation (DBS) is used to treat a wide array of neurologic conditions.
However, traditional programming of stimulation parameters relies upon short term …
However, traditional programming of stimulation parameters relies upon short term …
[HTML][HTML] Aberrant tonic inhibition of dopaminergic neuronal activity causes motor symptoms in animal models of Parkinson's disease
Current pharmacological treatments for Parkinson's disease (PD) are focused on
symptomatic relief, but not on disease modification, based on the strong belief that PD is …
symptomatic relief, but not on disease modification, based on the strong belief that PD is …
Frontiers in electrochemical sensors for neurotransmitter detection: towards measuring neurotransmitters as chemical diagnostics for brain disorders
It is extremely challenging to chemically diagnose disorders of the brain. There is hence
great interest in designing and optimizing tools for direct detection of chemical biomarkers …
great interest in designing and optimizing tools for direct detection of chemical biomarkers …
Tracking tonic dopamine levels in vivo using multiple cyclic square wave voltammetry
For over two decades, fast-scan cyclic voltammetry (FSCV) has served as a reliable
analytical method for monitoring dopamine release in near real-time in vivo. However …
analytical method for monitoring dopamine release in near real-time in vivo. However …
Direct in vivo electrochemical detection of resting dopamine using poly (3, 4-ethylenedioxythiophene)/carbon nanotube functionalized microelectrodes
IM Taylor, NA Patel, NC Freedman… - Analytical …, 2019 - ACS Publications
Dopamine (DA) is a monoamine neurotransmitter responsible for the maintenance of a
variety of vital life functions. In vivo DA signaling occurs over multiple time scales, from …
variety of vital life functions. In vivo DA signaling occurs over multiple time scales, from …
Stable in-vivo electrochemical sensing of tonic serotonin levels using PEDOT/CNT-coated glassy carbon flexible microelectrode arrays.
Chronic sampling of tonic serotonin (5-hydroxytryptamine, 5-HT) concentrations in the brain
is critical for tracking neurological disease development and the time course of …
is critical for tracking neurological disease development and the time course of …
3D fuzzy graphene microelectrode array for dopamine sensing at sub-cellular spatial resolution
The development of a high sensitivity real-time sensor for multi-site detection of dopamine
(DA) with high spatial and temporal resolution is of fundamental importance to study the …
(DA) with high spatial and temporal resolution is of fundamental importance to study the …
Evaluation of electrochemical methods for tonic dopamine detection in vivo
AE Rusheen, TA Gee, DP Jang, CD Blaha… - TrAC Trends in …, 2020 - Elsevier
Dysfunction in dopaminergic neuronal systems underlie a number of neurologic and
psychiatric disorders such as Parkinson's disease, drug addiction, and schizophrenia …
psychiatric disorders such as Parkinson's disease, drug addiction, and schizophrenia …